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4qrh

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<StructureSection load='4qrh' size='340' side='right'caption='[[4qrh]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4qrh' size='340' side='right'caption='[[4qrh]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4qrh]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_usa300-ismms1 Staphylococcus aureus usa300-ismms1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QRH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4qrh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_USA300-ISMMS1 Staphylococcus aureus USA300-ISMMS1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QRH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QRH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0O2:GUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)+3-(TRIHYDROGEN+DIPHOSPHATE)'>0O2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0O2:GUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)+3-(TRIHYDROGEN+DIPHOSPHATE)'>0O2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2j41|2j41]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qrh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qrh OCA], [https://pdbe.org/4qrh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qrh RCSB], [https://www.ebi.ac.uk/pdbsum/4qrh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qrh ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gmk, AZ30_05805 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1458279 Staphylococcus aureus USA300-ISMMS1])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_kinase Guanylate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.8 2.7.4.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qrh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qrh OCA], [http://pdbe.org/4qrh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qrh RCSB], [http://www.ebi.ac.uk/pdbsum/4qrh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qrh ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/W6E076_STAAU W6E076_STAAU]] Essential for recycling GMP and indirectly, cGMP.[HAMAP-Rule:MF_00328][SAAS:SAAS00152809]
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[https://www.uniprot.org/uniprot/A0A0J9X1Z9_STAAU A0A0J9X1Z9_STAAU]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Guanylate kinase|Guanylate kinase]]
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*[[Guanylate kinase 3D structures|Guanylate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guanylate kinase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staphylococcus aureus usa300-ismms1]]
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[[Category: Staphylococcus aureus USA300-ISMMS1]]
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[[Category: Keck, J L]]
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[[Category: Keck JL]]
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[[Category: Krasny, K]]
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[[Category: Krasny K]]
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[[Category: Liu, K]]
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[[Category: Liu K]]
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[[Category: Myers, A R]]
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[[Category: Myers AR]]
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[[Category: Satyshur, K A]]
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[[Category: Satyshur KA]]
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[[Category: Wnag, J D]]
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[[Category: Wnag JD]]
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[[Category: Phosphotransferase]]
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[[Category: Pppgpp]]
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[[Category: Transferase]]
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Revision as of 13:48, 22 February 2023

Molecular mechanism and evolution of guanylate kinase regulation by (p)ppGpp

PDB ID 4qrh

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