6oon
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==RNA-binding protein== | |
| - | + | <StructureSection load='6oon' size='340' side='right'caption='[[6oon]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6oon]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OON OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OON FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6oon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6oon OCA], [http://pdbe.org/6oon PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6oon RCSB], [http://www.ebi.ac.uk/pdbsum/6oon PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6oon ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/AGO4_HUMAN AGO4_HUMAN]] Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).[HAMAP-Rule:MF_03033]<ref>PMID:15337849</ref> <ref>PMID:18552826</ref> <ref>PMID:18771919</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brackbill, J A]] | ||
| + | [[Category: Nakanishi, K]] | ||
| + | [[Category: Park, M S]] | ||
| + | [[Category: Hydrolase-rna complex]] | ||
| + | [[Category: Mirna]] | ||
| + | [[Category: Rna]] | ||
| + | [[Category: Rna binding protein]] | ||
Revision as of 06:26, 31 July 2019
RNA-binding protein
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