6agt

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Current revision (09:30, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6agt' size='340' side='right'caption='[[6agt]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='6agt' size='340' side='right'caption='[[6agt]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6agt]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafo Plafo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AGT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6AGT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6agt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_NF54 Plasmodium falciparum NF54]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6AGT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6AGT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9X0:N-(cyclohexylmethyl)-4-oxo-4H-1-benzopyran-2-carboxamide'>9X0</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.953&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PFNF54_04763 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5843 PLAFO])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9X0:N-(cyclohexylmethyl)-4-oxo-4H-1-benzopyran-2-carboxamide'>9X0</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysine--tRNA_ligase Lysine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.6 6.1.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6agt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6agt OCA], [https://pdbe.org/6agt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6agt RCSB], [https://www.ebi.ac.uk/pdbsum/6agt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6agt ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6agt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6agt OCA], [http://pdbe.org/6agt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6agt RCSB], [http://www.ebi.ac.uk/pdbsum/6agt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6agt ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8IDJ8_PLAF7 Q8IDJ8_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6agt" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6agt" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lysine--tRNA ligase]]
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[[Category: Plasmodium falciparum NF54]]
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[[Category: Plafo]]
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[[Category: Baragana B]]
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[[Category: Baragana, B]]
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[[Category: Sharma A]]
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[[Category: Sharma, A]]
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[[Category: Walpole C]]
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[[Category: Walpole, C]]
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[[Category: Yogavel M]]
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[[Category: Yogavel, M]]
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[[Category: Aminoacylation]]
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[[Category: Atp binding protein]]
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[[Category: Chromone inhibitor]]
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[[Category: Kr]]
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[[Category: Ligase-inhibitor complex]]
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Current revision

Crystal structure of PfKRS complexed with chromone inhibitor

PDB ID 6agt

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