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4r7p

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<StructureSection load='4r7p' size='340' side='right'caption='[[4r7p]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
<StructureSection load='4r7p' size='340' side='right'caption='[[4r7p]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4r7p]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R7P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R7P FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4r7p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R7P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R7P FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UPG:URIDINE-5-DIPHOSPHATE-GLUCOSE'>UPG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3r2w|3r2w]], [[3r3i|3r3i]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r7p OCA], [https://pdbe.org/4r7p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r7p RCSB], [https://www.ebi.ac.uk/pdbsum/4r7p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r7p ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UGP2, UGP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UTP--glucose-1-phosphate_uridylyltransferase UTP--glucose-1-phosphate uridylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.9 2.7.7.9] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r7p OCA], [http://pdbe.org/4r7p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r7p RCSB], [http://www.ebi.ac.uk/pdbsum/4r7p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r7p ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/UGPA_HUMAN UGPA_HUMAN]] Plays a central role as a glucosyl donor in cellular metabolic pathways.
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[https://www.uniprot.org/uniprot/UGPA_HUMAN UGPA_HUMAN] Plays a central role as a glucosyl donor in cellular metabolic pathways.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: UTP--glucose-1-phosphate uridylyltransferase]]
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[[Category: Baruch P]]
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[[Category: Baruch, P]]
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[[Category: Cramer JT]]
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[[Category: Cramer, J T]]
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[[Category: Fedorov R]]
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[[Category: Fedorov, R]]
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[[Category: Fuehring J]]
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[[Category: Fuehring, J]]
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[[Category: Gerardy-Schahn R]]
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[[Category: Gerardy-Schahn, R]]
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[[Category: Schneider J]]
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[[Category: Schneider, J]]
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[[Category: Glc-1-p]]
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[[Category: Pyrophosphorylase]]
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[[Category: Rossmann-like alpha/beta/alpha sandwich fold]]
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[[Category: Transferase]]
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[[Category: Utp]]
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Revision as of 06:43, 2 March 2023

Human UDP-glucose pyrophosphorylase isoform 1 in complex with UDP-glucose

PDB ID 4r7p

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