4r52

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<StructureSection load='4r52' size='340' side='right'caption='[[4r52]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
<StructureSection load='4r52' size='340' side='right'caption='[[4r52]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4r52]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupmc Cupmc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R52 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R52 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4r52]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans_CH34 Cupriavidus metallidurans CH34]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R52 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">nbaC, nbaC Rmet_5193, Rmet_5193 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266264 CUPMC])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r52 OCA], [https://pdbe.org/4r52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r52 RCSB], [https://www.ebi.ac.uk/pdbsum/4r52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r52 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyanthranilate_3,4-dioxygenase 3-hydroxyanthranilate 3,4-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.11.6 1.13.11.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r52 OCA], [http://pdbe.org/4r52 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r52 RCSB], [http://www.ebi.ac.uk/pdbsum/4r52 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r52 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/3HAO_RALME 3HAO_RALME]] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.<ref>PMID:15909977</ref>
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[https://www.uniprot.org/uniprot/3HAO_CUPMC 3HAO_CUPMC] Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.[HAMAP-Rule:MF_00825]<ref>PMID:15909977</ref>
==See Also==
==See Also==
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*[[Dioxygenase|Dioxygenase]]
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*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-hydroxyanthranilate 3,4-dioxygenase]]
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[[Category: Cupriavidus metallidurans CH34]]
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[[Category: Cupmc]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Geng, J]]
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[[Category: Geng J]]
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[[Category: Gumpper, R H]]
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[[Category: Gumpper RH]]
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[[Category: Huo, L]]
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[[Category: Huo L]]
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[[Category: Liu, A]]
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[[Category: Liu A]]
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[[Category: Cupin rubredoxin]]
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[[Category: Oxidoreductase]]
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Revision as of 06:40, 2 March 2023

1.5 angstrom crystal structure of 3-hydroxyanthranilate-3,4-dioxygenase from Cupriavidus metallidurans

PDB ID 4r52

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