4rqx

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<StructureSection load='4rqx' size='340' side='right'caption='[[4rqx]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
<StructureSection load='4rqx' size='340' side='right'caption='[[4rqx]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4rqx]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RQX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4rqx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RQX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RQX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COM:1-THIOETHANESULFONIC+ACID'>COM</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COM:1-THIOETHANESULFONIC+ACID'>COM</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PRDX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rqx OCA], [https://pdbe.org/4rqx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rqx RCSB], [https://www.ebi.ac.uk/pdbsum/4rqx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rqx ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxiredoxin Peroxiredoxin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.15 1.11.1.15] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rqx OCA], [http://pdbe.org/4rqx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rqx RCSB], [http://www.ebi.ac.uk/pdbsum/4rqx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rqx ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRDX4_HUMAN PRDX4_HUMAN]] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.<ref>PMID:9388242</ref>
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[https://www.uniprot.org/uniprot/PRDX4_HUMAN PRDX4_HUMAN] Probably involved in redox regulation of the cell. Regulates the activation of NF-kappa-B in the cytosol by a modulation of I-kappa-B-alpha phosphorylation.<ref>PMID:9388242</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Peroxiredoxin|Peroxiredoxin]]
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*[[Peroxiredoxin 3D structures|Peroxiredoxin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peroxiredoxin]]
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[[Category: Badger J]]
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[[Category: Badger, J]]
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[[Category: Hausheer FH]]
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[[Category: Hausheer, F H]]
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[[Category: Logan C]]
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[[Category: Logan, C]]
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[[Category: Nienaber VL]]
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[[Category: Nienaber, V L]]
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[[Category: Sridhar V]]
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[[Category: Sridhar, V]]
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[[Category: Oxidoreductase]]
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[[Category: Thioredoxin]]
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Revision as of 08:24, 8 March 2023

Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA

PDB ID 4rqx

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