Cellobiohydrolase

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</StructureSection>
</StructureSection>
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==3D structures of cellobiohydrolase==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*Cellobiohydrolase I or exoglucanase 1
 
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**[[1cel]], [[4p1h]], [[4p1j]], [[5tc9]] – HjCBHI Cel7A catalytic domain – ''Hypocrea jecorina''<BR />
 
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**[[2cel]], [[4cel]], [[1egn]], [[1q2b]], [[5oa5]] - HjCBHI catalytic domain (mutant) <BR />
 
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**[[1cbh]], [[2cbh]], [[5x34]], [[5x35]], [[5x36]], [[5x37]], [[5x38]] – HjCBHI C terminal – NMR<BR />
 
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**[[5x3c]], [[5x39]] – HjCBHI C terminal (mutant) – NMR<br />
 
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**[[1azh]], [[1az6]], [[1azj]], [[1azk]] - HjCBHI cellulose-binding domain (mutant) - NMR<BR />
 
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**[[1gpi]] - PcCBHI Cel7D catalytic domain – ''Phanerochaete chrysosporium''<BR />
 
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**[[1q9h]], [[3pfj]] - TeCBHI Cel7A catalytic domain – ''Talaromyces emersonii''<BR />
 
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**[[2yok]], [[2y9n]] - CBHI Cel7A catalytic domain – ''Hypocrea lixii''<br />
 
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**[[5mcc]], [[5mcd]], [[5mce]], [[5mcf]], [[5mch]], [[5mci]], [[5mcj]], [[5mck]], [[5mcl]], [[5mcm]], [[5mcn]], [[4xnn]] – wfCBHI – water flea<br />
 
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**[[4zzv]], [[5amp]] - GcCBHI Cel7A catalytic domain – ''Galactomyces candidum''<br />
 
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**[[2mwk]], [[2mwj]] - TrCBHI Cel7A carbohydrate-binding module 1 domain – ''Trichoderma reesei''<br />
 
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**[[4v1z]] – AfCBH Cel7A – ''Aspergillus fumigatus''<br />
 
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*''Cellobiohydrolase I binary complex''
 
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**[[3cel]], [[4uwt]] - HjCBHI Cel7A catalytic domain (mutant) + cellobiose<br />
 
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**[[5cel]], [[1q2e]], [[4d5v]] - HjCBHI Cel7A catalytic domain (mutant) + cellotetraose<br />
 
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**[[4d5q]] - HjCBHI Cel7A catalytic domain + cellopentaose<br />
 
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**[[6cel]], [[4d5o]], [[4d5p]] - HjCBHI Cel7A catalytic domain (mutant) + cellopentaose<br />
 
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**[[7cel]] - HjCBHI catalytic domain (mutant) + glucose<br />
 
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**[[2v3i]], [[2v3r]] - HjCBHI Cel7A catalytic domain + phenanthrenolol<br />
 
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**[[1dy4]], [[6grn]] - TrCBHI Cel7A catalytic domain + propranolol derivative<BR />
 
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**[[4v0z]] - TrCBH Cel7A catalytic domain + cellobiose<br />
 
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**[[4vwt]] - TrCBH Cel7A (mutant) catsalytic domain + cellobiose<br />
 
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**[[4c4c]] - TrCBHI Cel7A catalytic domain (mutant) + cellononaose <br />
 
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**[[4c4d]], [[4d5i]], [[4d5j]] - TrCBHI Cel7A catalytic domain (mutant) + cellotrioside <br />
 
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**[[3pfx]] - TeCBHI Cel7A catalytic domain + cellobiose<br />
 
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**[[3pfz]] - TeCBHI Cel7A catalytic domain + cellotetraose + cellobiose<br />
 
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**[[3pl3]] - TeCBHI Cel7A catalytic domain + cellopentaose<br />
 
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**[[4zzu]] - GgCBHI Cel7A catalytic domain + cellotetraose – ''Galactomyces geotrichum''<br />
 
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**[[4zzw]] - GgCBHI Cel7A catalytic domain + cellobiose <br />
 
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**[[4zzt]] - GcCBHI Cel7A catalytic domain + cellotraiose <br />
 
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**[[5w11]] - CBHI Cel7A catalytic domain + cellotriose – ''Myceliophthota thermophila''<br />
 
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**[[5o5d]] - HaCBHI Cel7A catalytic domain – ''Hypocrea atroviridis''<br />
 
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**[[5o59]] - HaCBHI Cel7A catalytic domain + glucose <br />
 
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**[[4v20]] - AfCBH Cel7A catalytic domain + disaccharide<br />
 
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**[[1h46]] - PcCBHI Cel7D catalytic domain + propranolol<br />
 
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**[[1z3t]] - PcCBHI Cel7D catalytic domain + cellobiose<br />
 
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**[[1z3v]] - PcCBHI Cel7D catalytic domain + lactose<br />
 
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**[[1z3w]] - PcCBHI Cel7D catalytic domain + cellobioimidazole<BR />
 
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*Cellobiohydrolase II or Cellobiohydrolase Cel6A or exoglucanase 2
 
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**[[3cbh]] – HjCBHII core<BR />
 
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**[[1cb2]] – HjCBHII catalytic domain (mutant) <BR />
 
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**[[1hgw]], [[1hgy]], [[1oc6]] – HjCBHII Cel6A catalytic domain (mutant)
 
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*''Cellobiohydrolase II complex''
 
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**[[1bvw]] - HiCBHII catalytic domain + mannose – ''Humicola insolens''<BR />
 
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**[[4au0]] - HjCBHII catalytic domain Cel6A (mutant) + cellobioside<br />
 
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**[[2bvw]] - HiCBHII Cel6A catalytic domain + glucose + cellotetraose<br />
 
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**[[1gz1]], [[1oc5]] - HiCBHII Cel6A catalytic domain (mutant) + cellotetraose<br />
 
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**[[1oc7]] - HiCBHII Cel6A catalytic domain (mutant) + cellopentaose<br />
 
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**[[1ocj]] - HiCBHII Cel6A catalytic domain + cellopentaose<br />
 
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**[[1ocb]] - HiCBHII Cel6A catalytic domain + fluorescent substrate<BR />
 
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**[[1ocn]] - HiCBHII Cel6A catalytic domain (mutant) + isofagomine<BR />
 
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**[[1qjw]] - TrCBHII Cel6A catalytic domain (mutant) + cellotetraose<br />
 
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**[[4ax6]], [[4ax7]] - TrCBHII Cel6A catalytic domain (mutant) + cellobioside<br />
 
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**[[1qk0]] - TrCBHII Cel6A catalytic domain + polysaccharide<BR />
 
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**[[1qk2]] - TrCBHII Cel6A catalytic domain + cellotetraose<br />
 
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**[[4a05]] - CBHII Cel6A catalytic domain + cellotetraose – ''Chaetonium thermophilum''<br />
 
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*Other cellobiohydrolases
 
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**[[1l1y]] – CtCBH CelS – ''Clostridium thermocellum''<BR />
 
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**[[1rq5]] - CtCBHA (mutant) <BR />
 
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**[[1ut9]] - CtCBHA catalytic domain<BR />
 
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**[[1sqj]] - GgCBH <BR />
 
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**[[3a64]], [[3vog]] - CcCBH Cel6C catalytic domain - ''Coprinopsis cinerea''<BR />
 
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**[[3vof]], [[3voj]] - CcCBHI Cel6C catalytic domain (mutant)<br />
 
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**[[2mte]] – CBH CelS residues 673-741 – ''Ruminiclostridium thermocellum'' - NMR<br />
 
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*''Other cellobiohydrolases binary complex''
 
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**[[1l2a]] - CtCBH CelS + glucose<br />
 
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**[[2ebs]] – GgCBH (mutant) + heptasaccharide<BR />
 
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**[[4avn]] - CBH Cel6B + cellobiose – Thermobifidia fusca<br />
 
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**[[3a9b]], [[3voh]] - CcCBHI Cel6C catalytic domain + cellobiose<br />
 
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**[[3abx]], [[3voi]] - CcCBHI Cel6C catalytic domain + cellotriose<br />
 
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**[[4v20]] - AfCBH Cel7A + disaccharide<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 09:46, 5 May 2019

Glycosylated cellobiohydrolase I catalytic domain complex with cellobiose and Cd+2 ions (PDB code 3cel)

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References

  1. ↑ Divne C, Stahlberg J, Teeri TT, Jones TA. High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei. J Mol Biol. 1998 Jan 16;275(2):309-25. PMID:9466911 doi:http://dx.doi.org/10.1006/jmbi.1997.1437
  2. ↑ Stahlberg J, Divne C, Koivula A, Piens K, Claeyssens M, Teeri TT, Jones TA. Activity studies and crystal structures of catalytically deficient mutants of cellobiohydrolase I from Trichoderma reesei. J Mol Biol. 1996 Nov 29;264(2):337-49. PMID:8951380 doi:http://dx.doi.org/10.1006/jmbi.1996.0644

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Michal Harel, Alexander Berchansky, Karsten Theis

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