This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4tps

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 3: Line 3:
<StructureSection load='4tps' size='340' side='right'caption='[[4tps]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='4tps' size='340' side='right'caption='[[4tps]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4tps]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TPS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TPS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4tps]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TPS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TPS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sirA, yneE, yoxF, BSU17900 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU]), dnaA, dnaH, BSU00010 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tps OCA], [https://pdbe.org/4tps PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tps RCSB], [https://www.ebi.ac.uk/pdbsum/4tps PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tps ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tps FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tps OCA], [http://pdbe.org/4tps PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tps RCSB], [http://www.ebi.ac.uk/pdbsum/4tps PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tps ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/SIRA_BACSU SIRA_BACSU]] Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation. [[http://www.uniprot.org/uniprot/DNAA_BACSU DNAA_BACSU]] Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. DnaA can inhibit its own gene expression as well as that of other genes.
+
[https://www.uniprot.org/uniprot/SIRA_BACSU SIRA_BACSU] Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 19: Line 18:
</div>
</div>
<div class="pdbe-citations 4tps" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4tps" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[DnaA|DnaA]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bacsu]]
+
[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Fogg, M J]]
+
[[Category: Fogg MJ]]
-
[[Category: Grahl, A]]
+
[[Category: Grahl A]]
-
[[Category: Jameson, K H]]
+
[[Category: Jameson KH]]
-
[[Category: Turkenburg, J P]]
+
[[Category: Turkenburg JP]]
-
[[Category: Wilkinson, A J]]
+
[[Category: Wilkinson AJ]]
-
[[Category: Inhibitory complex]]
+
-
[[Category: Replication]]
+
-
[[Category: Sporulation]]
+

Revision as of 10:48, 15 March 2023

Sporulation Inhibitor of DNA Replication, SirA, in complex with Domain I of DnaA

PDB ID 4tps

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4tps"
Personal tools