This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Cholesterol esterase
From Proteopedia
(Difference between revisions)
| Line 11: | Line 11: | ||
ChoE <scene name='52/525136/Cv/9'>ligand-binding tunnel is ca. 30 A long</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). ChoE has the <scene name='52/525136/Cv/10'>polar catalytic triad Ser-His-Glu</scene> at the opening and <scene name='52/525136/Cv/11'>hydrophobic residues lining the bottom cup</scene>.<ref>PMID:12499539</ref> | ChoE <scene name='52/525136/Cv/9'>ligand-binding tunnel is ca. 30 A long</scene> ({{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}). ChoE has the <scene name='52/525136/Cv/10'>polar catalytic triad Ser-His-Glu</scene> at the opening and <scene name='52/525136/Cv/11'>hydrophobic residues lining the bottom cup</scene>.<ref>PMID:12499539</ref> | ||
| + | |||
| + | ==3D structures of cholesterol esterase== | ||
| + | [[Cholesterol esterase 3D structures]] | ||
| + | |||
</StructureSection> | </StructureSection> | ||
==3D structures of cholesterol esterase== | ==3D structures of cholesterol esterase== | ||
| Line 19: | Line 23: | ||
*Cholesterol esterase | *Cholesterol esterase | ||
| + | **[[1jmy]] – hChoE catalytic domain- human<br /> | ||
| + | **[[1f6w]], [[6h0t]] – hChoE catalytic domain (mutant) <br /> | ||
**[[1akn]] – bChoE – bovine<br /> | **[[1akn]] – bChoE – bovine<br /> | ||
**[[2bce]] – bChoE (mutant)<br /> | **[[2bce]] – bChoE (mutant)<br /> | ||
| - | **[[1jmy]] – hChoE - human<br /> | ||
| - | **[[1f6w]] – hChoE catalytic domain (mutant) <br /> | ||
**[[4be9]], [[4be4]] – OpChoE – ''Ophiostoma piceae''<br /> | **[[4be9]], [[4be4]] – OpChoE – ''Ophiostoma piceae''<br /> | ||
**[[4upd]] – OpChoE (mutant) <br /> | **[[4upd]] – OpChoE (mutant) <br /> | ||
| - | *Cholesterol esterase complex | + | *Cholesterol esterase complex |
| + | **[[6h0v]] – hChoE (mutant) + tabun<br /> | ||
| + | **[[6h18]] – hChoE (mutant) + sarin<br /> | ||
| + | **[[6h19]] – hChoE (mutant) + paraoxon<br /> | ||
| + | **[[6h1a]] – hChoE (mutant) + VX<br /> | ||
| + | **[[1aql]] – bChoE + taurocholate<br /> | ||
**[[1cle]] – CcChoE + cholesteryl linoleate – ''Candida cylindracea''<br /> | **[[1cle]] – CcChoE + cholesteryl linoleate – ''Candida cylindracea''<br /> | ||
**[[1llf]] – CcChoE + tricosanoic acid<br /> | **[[1llf]] – CcChoE + tricosanoic acid<br /> | ||
| - | + | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:16, 12 May 2019
| |||||||||||
3D structures of cholesterol esterase
Updated on 12-May-2019
References
- ↑ Moore SA, Kingston RL, Loomes KM, Hernell O, Blackberg L, Baker HM, Baker EN. The structure of truncated recombinant human bile salt-stimulated lipase reveals bile salt-independent conformational flexibility at the active-site loop and provides insights into heparin binding. J Mol Biol. 2001 Sep 21;312(3):511-23. PMID:11563913 doi:10.1006/jmbi.2001.4979
- ↑ Pletnev V, Addlagatta A, Wawrzak Z, Duax W. Three-dimensional structure of homodimeric cholesterol esterase-ligand complex at 1.4 A resolution. Acta Crystallogr D Biol Crystallogr. 2003 Jan;59(Pt 1):50-6. Epub 2002 Dec, 19. PMID:12499539
