Inorganic pyrophosphatase

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== Structural highlights ==
== Structural highlights ==
The biological assembly of Inorganic pyrophosphatase ''Helicobacter pylori'' is <scene name='48/488499/Cv/6'>homohexamer</scene>. PPase <scene name='48/488499/Cv/7'>binding pocket has electrostatic potential and is composed of 3 lysine residues, a tyrosine and several water molecules</scene><ref>PMID:16988955</ref>. {{Template:ColorKey_Charge_Anionic}} / {{Template:ColorKey_Charge_Cationic}}. Water molecules shown as red spheres.
The biological assembly of Inorganic pyrophosphatase ''Helicobacter pylori'' is <scene name='48/488499/Cv/6'>homohexamer</scene>. PPase <scene name='48/488499/Cv/7'>binding pocket has electrostatic potential and is composed of 3 lysine residues, a tyrosine and several water molecules</scene><ref>PMID:16988955</ref>. {{Template:ColorKey_Charge_Anionic}} / {{Template:ColorKey_Charge_Cationic}}. Water molecules shown as red spheres.
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==3D structures of inorganic pyrophosphatase==
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[[Inorganic pyrophosphatase 3D structures]]
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</StructureSection>
</StructureSection>
==3D structures of inorganic pyrophosphatase==
==3D structures of inorganic pyrophosphatase==
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*Pyrophosphatase
*Pyrophosphatase
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**[[6c45]] – PPase – human<br />
**[[1pyp]] – yPPase – yeast<br />
**[[1pyp]] – yPPase – yeast<br />
**[[1igp]], [[1faj]], [[2eip]], [[1jfd]], [[4um4]] – EcPPase – ''Escherichia coli''<br />
**[[1igp]], [[1faj]], [[2eip]], [[1jfd]], [[4um4]] – EcPPase – ''Escherichia coli''<br />
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**[[3q3l]] – TtPPase – neutron diffraction<br />
**[[3q3l]] – TtPPase – neutron diffraction<br />
**[[4lug]], [[5ls0]] - PPase – ''Arabidopsis thaliana''<br />
**[[4lug]], [[5ls0]] - PPase – ''Arabidopsis thaliana''<br />
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**[[6mt1]], [[6mt2]] – PPase – ''Medicago truncatula''<br />
*Pyrophosphatase binary complex
*Pyrophosphatase binary complex
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**[[1ino]] – EcPPase + Mn<br />
 
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**[[1ipw]], [[1obw]] - EcPPase + Mg<br />
 
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**[[1i40]] - EcPPase + Ca<br />
 
**[[1wgi]] - yPPase + Mn<br />
**[[1wgi]] - yPPase + Mn<br />
**[[1huk]] - yPPase + Mg<br />
**[[1huk]] - yPPase + Mg<br />
**[[1huj]], [[2ik1]] - yPPase (mutant) + Mg<br />
**[[1huj]], [[2ik1]] - yPPase (mutant) + Mg<br />
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**[[1ino]] – EcPPase + Mn<br />
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**[[1ipw]], [[1obw]] - EcPPase + Mg<br />
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**[[1i40]] - EcPPase + Ca<br />
**[[1qez]] - PPase + Mg – ''Sulfolobus acidocaldarius''<br />
**[[1qez]] - PPase + Mg – ''Sulfolobus acidocaldarius''<br />
**[[3r5u]] – TtPPase + Mn <br />
**[[3r5u]] – TtPPase + Mn <br />
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**[[5tea]] – PPase + Ca – ''Neisseria gonorrhieae''<br />
**[[5tea]] – PPase + Ca – ''Neisseria gonorrhieae''<br />
**[[5h4f]] - PPase + Zn – synthetic<br />
**[[5h4f]] - PPase + Zn – synthetic<br />
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**[[6n1c]] - PPase + Ala – ''Legionella pneumophila''<br />
*Pyrophosphatase ternary complex
*Pyrophosphatase ternary complex

Revision as of 08:15, 28 August 2019

Inorganic pyrophosphatase complex with pyrophosphate, 2bqy

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3D structures of inorganic pyrophosphatase

Updated on 28-August-2019

References

  1. Harold FM. Inorganic polyphosphates in biology: structure, metabolism, and function. Bacteriol Rev. 1966 Dec;30(4):772-94. PMID:5342521
  2. Chao TC, Huang H, Tsai JY, Huang CY, Sun YJ. Kinetic and structural properties of inorganic pyrophosphatase from the pathogenic bacterium Helicobacter pylori. Proteins. 2006 Nov 15;65(3):670-80. PMID:16988955 doi:10.1002/prot.21093

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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