This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6jxh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6jxh is ON HOLD until Paper Publication
+
==K+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)==
-
 
+
<StructureSection load='6jxh' size='340' side='right'caption='[[6jxh]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
Authors: Abe, K., Irie, K.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[6jxh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JXH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JXH FirstGlance]. <br>
-
Description: K+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CE1:O-DODECANYL+OCTAETHYLENE+GLYCOL'>CE1</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MF4:TETRAFLUOROMAGNESATE(2-)'>MF4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)/K(+)-exchanging_ATPase H(+)/K(+)-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=7.2.2.19 7.2.2.19] </span></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jxh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jxh OCA], [http://pdbe.org/6jxh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jxh RCSB], [http://www.ebi.ac.uk/pdbsum/6jxh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jxh ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[[http://www.uniprot.org/uniprot/ATP4B_PIG ATP4B_PIG]] Note=Parietal cell autoantigen associated with autoimmune gastritis.
 +
== Function ==
 +
[[http://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Abe, K]]
[[Category: Irie, K]]
[[Category: Irie, K]]
-
[[Category: Abe, K]]
+
[[Category: Gastric]]
 +
[[Category: Ion pump]]
 +
[[Category: Membrane protein]]
 +
[[Category: P-type atpase]]
 +
[[Category: Proton pump]]

Revision as of 16:34, 14 August 2019

K+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)

PDB ID 6jxh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools