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4wau

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<StructureSection load='4wau' size='340' side='right'caption='[[4wau]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4wau' size='340' side='right'caption='[[4wau]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WAU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wau]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WAU FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4p0t|4p0t]]</td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wau OCA], [https://pdbe.org/4wau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wau RCSB], [https://www.ebi.ac.uk/pdbsum/4wau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wau ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CENPM, C22orf18, ICEN39, PANE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wau OCA], [http://pdbe.org/4wau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wau RCSB], [http://www.ebi.ac.uk/pdbsum/4wau PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wau ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CENPM_HUMAN CENPM_HUMAN]] Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.<ref>PMID:16716197</ref>
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[https://www.uniprot.org/uniprot/CENPM_HUMAN CENPM_HUMAN] Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.<ref>PMID:16716197</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Basilico, F]]
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[[Category: Basilico F]]
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[[Category: Cecatiello, V]]
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[[Category: Cecatiello V]]
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[[Category: Pasqualato, S]]
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[[Category: Pasqualato S]]
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[[Category: Wang, M]]
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[[Category: Wang M]]
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[[Category: Weinert, T]]
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[[Category: Weinert T]]
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[[Category: Ccan]]
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[[Category: Cell cycle]]
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[[Category: G-protein]]
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[[Category: Kinetochore]]
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[[Category: Mitosis]]
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[[Category: Native-sad]]
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[[Category: S-sad]]
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[[Category: Sulfur sad]]
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[[Category: Sulfur-sad]]
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Revision as of 07:00, 7 April 2023

Crystal structure of CENP-M solved by native-SAD phasing

PDB ID 4wau

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