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4wz5

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Current revision (21:04, 12 April 2023) (edit) (undo)
 
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<StructureSection load='4wz5' size='340' side='right'caption='[[4wz5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4wz5' size='340' side='right'caption='[[4wz5]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4wz5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WZ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WZ5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4wz5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WZ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WZ5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3VU:{(3R)-6-[(3-AMINO-1,2,4-THIADIAZOL-5-YL)OXY]-1-HYDROXY-4,5-DIMETHYL-1,3-DIHYDRO-2,1-BENZOXABOROL-3-YL}ACETIC+ACID'>3VU</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3VU:{(3R)-6-[(3-AMINO-1,2,4-THIADIAZOL-5-YL)OXY]-1-HYDROXY-4,5-DIMETHYL-1,3-DIHYDRO-2,1-BENZOXABOROL-3-YL}ACETIC+ACID'>3VU</scene>, <scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wz5 OCA], [https://pdbe.org/4wz5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wz5 RCSB], [https://www.ebi.ac.uk/pdbsum/4wz5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wz5 ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wyy|4wyy]], [[4wz4|4wz4]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla, oxa10, pse2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wz5 OCA], [http://pdbe.org/4wz5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wz5 RCSB], [http://www.ebi.ac.uk/pdbsum/4wz5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wz5 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BLO10_PSEAI BLO10_PSEAI]] Hydrolyzes both carbenicillin and oxacillin.
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[https://www.uniprot.org/uniprot/BLO10_PSEAI BLO10_PSEAI] Hydrolyzes both carbenicillin and oxacillin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ferguson, A D]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Beta lactamase]]
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[[Category: Ferguson AD]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Inhibtor]]
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Current revision

Crystal structure of P. aeruginosa OXA10

PDB ID 4wz5

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