Journal:Acta Cryst D:S2059798319006995
From Proteopedia
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<scene name='81/816443/Cv/3'>Overall structure of HuA21 scFv in complex with HER2 ECD</scene>. In ECD, the subdomains I, II, III and IV are colored red, green, blue and yellow, respectively. The light chain (V<sub>L</sub>) and heavy chain (V<sub>H</sub>) of HuA21 scFv are colored magenta and cyan, respectively. <scene name='81/816443/Cv/4'>HuA21 consists of two immunoglobulin domains formed by the VH and VL fragments</scene>, respectively. <scene name='81/816443/Cv/5'>The extracellular domain of HER2 is composed of four subdomains designated I, II, III and IV</scene>. | <scene name='81/816443/Cv/3'>Overall structure of HuA21 scFv in complex with HER2 ECD</scene>. In ECD, the subdomains I, II, III and IV are colored red, green, blue and yellow, respectively. The light chain (V<sub>L</sub>) and heavy chain (V<sub>H</sub>) of HuA21 scFv are colored magenta and cyan, respectively. <scene name='81/816443/Cv/4'>HuA21 consists of two immunoglobulin domains formed by the VH and VL fragments</scene>, respectively. <scene name='81/816443/Cv/5'>The extracellular domain of HER2 is composed of four subdomains designated I, II, III and IV</scene>. | ||
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| + | The Interface of the HuA21-HER2 Complex | ||
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| + | <scene name='81/816443/Cv/8'>The CDRs</scene> are labelled L1, L2, L3, H1, H2 and H3 and colored paleyellow, limegreen, lightorange, palegreen, palecyan and lightpink, respectively. The other parts of HuA21 scFv are colored light gray. | ||
<b>References</b><br> | <b>References</b><br> | ||
Revision as of 12:55, 23 May 2019
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This page complements a publication in scientific journals and is one of the Proteopedia's Interactive 3D Complement pages. For aditional details please see I3DC.
