6jp1
From Proteopedia
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<StructureSection load='6jp1' size='340' side='right'caption='[[6jp1]], [[Resolution|resolution]] 1.99Å' scene=''> | <StructureSection load='6jp1' size='340' side='right'caption='[[6jp1]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[6jp1]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JP1 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6jp1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Phymc Phymc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JP1 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9755 PHYMC])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jp1 OCA], [http://pdbe.org/6jp1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jp1 RCSB], [http://www.ebi.ac.uk/pdbsum/6jp1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jp1 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jp1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jp1 OCA], [http://pdbe.org/6jp1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jp1 RCSB], [http://www.ebi.ac.uk/pdbsum/6jp1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jp1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | [[http://www.uniprot.org/uniprot/MYG_PHYMC MYG_PHYMC]] Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The X-ray crystal structure of F43Y/T67R myoglobin revealed unique Tyr-heme double cross-links between Tyr43 and the heme 4-vinyl group, which represents a novel post-translational modification of heme proteins. Moreover, with the feature of a distal His-Arg pair, the designed artificial enzyme exhibited a peroxidase activity comparable to that of native peroxidases, such as the most efficient horseradish peroxidase. | ||
| + | |||
| + | Unique Tyr-heme double cross-links in F43Y/T67R myoglobin: an artificial enzyme with a peroxidase activity comparable to that of native peroxidases.,Liu C, Yuan H, Liao F, Wei CW, Du KJ, Gao SQ, Tan X, Lin YW Chem Commun (Camb). 2019 Jun 11;55(46):6610-6613. doi: 10.1039/c9cc02714a. Epub, 2019 May 23. PMID:31119219<ref>PMID:31119219</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 6jp1" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Phymc]] | ||
[[Category: Lin, Y W]] | [[Category: Lin, Y W]] | ||
[[Category: Yuan, H]] | [[Category: Yuan, H]] | ||
Revision as of 06:31, 19 June 2019
An X-ray structure of met sperm whale F43Y/T67R myoglobin with Tyr-heme double cross-links
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