This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Integrin
From Proteopedia
(Difference between revisions)
| Line 12: | Line 12: | ||
<scene name='51/516472/Cv/4'>Mg/Cl coordination site</scene>. Water molecules shown as red spheres. | <scene name='51/516472/Cv/4'>Mg/Cl coordination site</scene>. Water molecules shown as red spheres. | ||
| + | |||
| + | ==3D structures of integrin== | ||
| + | [[Integrin 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
| Line 75: | Line 78: | ||
**[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br /> | **[[1dzi]], [[4bj3]] - hIG I domain + collagen peptide<br /> | ||
**[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br /> | **[[1v7p]] - hIG I domain (mutant) + EMS16 + Mn<br /> | ||
| - | **[[5thp]] - hIG residues 170-366 + rhodocetin <br /> | + | **[[5thp]], [[6nd8]], [[6nd9]], [[6nda]], [[6ndb]], [[6ndc]], [[6ndd]], [[6nde]], [[6ndf]], [[6ndg]], [[6ndh]] - hIG residues 170-366 + rhodocetin <br /> |
*IG α-2b | *IG α-2b | ||
| Line 153: | Line 156: | ||
**[[2lke]], [[2lkj]] – hIG cytoplasmic domain – NMR<BR /> | **[[2lke]], [[2lkj]] – hIG cytoplasmic domain – NMR<BR /> | ||
**[[4xw2]] – hIG + simvastatin<br /> | **[[4xw2]] – hIG + simvastatin<br /> | ||
| + | |||
| + | *IG α-V β-8 | ||
| + | |||
| + | **[[6djp]] – hIG + antibody – Cryo EM<br /> | ||
*IG α-X | *IG α-X | ||
| Line 171: | Line 178: | ||
**[[2p26]], [[2p28]], [[5e6w]] – hIG phe2 + phe3 domains<br /> | **[[2p26]], [[2p28]], [[5e6w]] – hIG phe2 + phe3 domains<br /> | ||
**[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br /> | **[[1yuk]] – hIG chain A PSI domain + chain B I-EGF domain<br /> | ||
| + | **[[5zaz]] – hIG transmembrane domain - NMR<br /> | ||
*IG β-3 (CD61) | *IG β-3 (CD61) | ||
| Line 180: | Line 188: | ||
**[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br /> | **[[2mtp]] – hIG cytoplasmic tail (mutant) + hIG α-2 β peptide+ filamin rod domain<br /> | ||
| - | *IG β-4 (CD104) | + | *IG β-4 (CD104; Gp150) |
**[[2f7q]], [[3f7r]], [[1qg3]], [[3f7q]], [[4wtw]], [[4wtx]] - hIG fibronectin type III domain<br /> | **[[2f7q]], [[3f7r]], [[1qg3]], [[3f7q]], [[4wtw]], [[4wtx]] - hIG fibronectin type III domain<br /> | ||
**[[2yrz]] – hIG fibronectin type III domain – NMR<BR /> | **[[2yrz]] – hIG fibronectin type III domain – NMR<BR /> | ||
**[[3f7p]], [[4q58]] - hIG fibronectin type III domain + plectin-1 <br /> | **[[3f7p]], [[4q58]] - hIG fibronectin type III domain + plectin-1 <br /> | ||
| - | **[[3fq4]], [[3fso]], [[3h6a]] – hIG Calx-β domain | + | **[[6gvl]] - hIG fibronectin type III domain + dystonin<br /> |
| + | **[[6gvk]] - hIG fibronectin type III domain (mutant) + dystonin<br /> | ||
| + | **[[3fq4]], [[3fso]], [[3h6a]] – hIG Calx-β domain<br /> | ||
| + | **[[6hyf]] - rIG fibronectin type III domain <br /> | ||
*IG β-7 | *IG β-7 | ||
Revision as of 10:23, 29 August 2019
| |||||||||||
3D structures of integrin
Updated on 29-August-2019
References
- ↑ Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914
- ↑ Hillis GS, MacLeod AM. Integrins and disease. Clin Sci (Lond). 1996 Dec;91(6):639-50. PMID:8976799
- ↑ Larjava H, Koivisto L, Heino J, Hakkinen L. Integrins in periodontal disease. Exp Cell Res. 2014 Jul 15;325(2):104-10. doi: 10.1016/j.yexcr.2014.03.010. Epub, 2014 Mar 22. PMID:24662197 doi:http://dx.doi.org/10.1016/j.yexcr.2014.03.010
- ↑ Humphries MJ. Integrin structure. Biochem Soc Trans. 2000;28(4):311-39. PMID:10961914
