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5zje
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==LDHA-mla== | |
| - | + | <StructureSection load='5zje' size='340' side='right'caption='[[5zje]], [[Resolution|resolution]] 2.93Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5zje]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZJE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZJE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr> | |
| - | [[Category: | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27] </span></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zje OCA], [http://pdbe.org/5zje PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zje RCSB], [http://www.ebi.ac.uk/pdbsum/5zje PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zje ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/LDHA_HUMAN LDHA_HUMAN]] Defects in LDHA are the cause of glycogen storage disease type 11 (GSD11) [MIM:[http://omim.org/entry/612933 612933]]. A metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.<ref>PMID:2334430</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: L-lactate dehydrogenase]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Han, C W]] | ||
| + | [[Category: Jang, S B]] | ||
| + | [[Category: Ldha wt]] | ||
| + | [[Category: Malonate]] | ||
| + | [[Category: Oxidoreductase]] | ||
Revision as of 06:04, 24 July 2019
LDHA-mla
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