2j47

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2j47.gif|left|200px]]<br />
+
[[Image:2j47.gif|left|200px]]<br /><applet load="2j47" size="450" color="white" frame="true" align="right" spinBox="true"
-
<applet load="2j47" size="450" color="white" frame="true" align="right" spinBox="true"
+
caption="2j47, resolution 1.98&Aring;" />
caption="2j47, resolution 1.98&Aring;" />
'''BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH A IMIDAZOLE-PUGNAC HYBRID INHIBITOR'''<br />
'''BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH A IMIDAZOLE-PUGNAC HYBRID INHIBITOR'''<br />
Line 8: Line 7:
==About this Structure==
==About this Structure==
-
2J47 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron] with GDV and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J47 OCA].
+
2J47 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron] with GDV and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] Known structural/functional Site: <scene name='pdbsite=AC1:Gdv Binding Site For Chain A'>AC1</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2J47 OCA].
==Reference==
==Reference==
Line 27: Line 26:
[[Category: pugnac]]
[[Category: pugnac]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 18:24:46 2007''
+
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 19:47:53 2007''

Revision as of 17:38, 18 December 2007

Image:2j47.gif

2j47, resolution 1.98Å

Drag the structure with the mouse to rotate

BACTEROIDES THETAIOTAOMICRON GH84 O-GLCNACASE IN COMPLEX WITH A IMIDAZOLE-PUGNAC HYBRID INHIBITOR

Overview

Synthesis of a PUGNAc-imidazole hybrid and its characterization as an, inhibitor of human O-GlcNAcase through enzyme kinetics and X-ray, structural analysis.

About this Structure

2J47 is a Single protein structure of sequence from Bacteroides thetaiotaomicron with GDV and GOL as ligands. Active as Beta-N-acetylhexosaminidase, with EC number 3.2.1.52 Known structural/functional Site: . Full crystallographic information is available from OCA.

Reference

Inhibition of O-GlcNAcase by a gluco-configured nagstatin and a PUGNAc-imidazole hybrid inhibitor., Shanmugasundaram B, Debowski AW, Dennis RJ, Davies GJ, Vocadlo DJ, Vasella A, Chem Commun (Camb). 2006 Nov 13;(42):4372-4. Epub 2006 Sep 29. PMID:17057847

Page seeded by OCA on Tue Dec 18 19:47:53 2007

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2j47"
Personal tools