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5krr

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Current revision (10:52, 27 September 2023) (edit) (undo)
 
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<StructureSection load='5krr' size='340' side='right'caption='[[5krr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='5krr' size='340' side='right'caption='[[5krr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5krr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibvu Vibvu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KRR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KRR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5krr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_vulnificus_CMCP6 Vibrio vulnificus CMCP6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KRR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5kqo|5kqo]], [[5krv|5krv]], [[5kry|5kry]], [[5ks1|5ks1]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dxr, VV1_1866 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=216895 VIBVU])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5krr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5krr OCA], [https://pdbe.org/5krr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5krr RCSB], [https://www.ebi.ac.uk/pdbsum/5krr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5krr ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-deoxy-D-xylulose-5-phosphate_reductoisomerase 1-deoxy-D-xylulose-5-phosphate reductoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.267 1.1.1.267] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5krr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5krr OCA], [http://pdbe.org/5krr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5krr RCSB], [http://www.ebi.ac.uk/pdbsum/5krr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5krr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DXR_VIBVU DXR_VIBVU]] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
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[https://www.uniprot.org/uniprot/DXR_VIBVU DXR_VIBVU] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[DXP reductoisomerase|DXP reductoisomerase]]
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*[[DXP reductoisomerase 3D Structures|DXP reductoisomerase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Vibvu]]
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[[Category: Vibrio vulnificus CMCP6]]
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[[Category: Abdulsalam, R W]]
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[[Category: Abdulsalam RW]]
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[[Category: Chruszcz, M]]
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[[Category: Chruszcz M]]
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[[Category: Offermann, L R]]
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[[Category: Offermann LR]]
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[[Category: Perdue, M]]
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[[Category: Perdue M]]
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[[Category: Ussin, N]]
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[[Category: Ussin N]]
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[[Category: Dxr 1-deoxy-d-xylulose 5-phosphate reductoisomerase]]
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[[Category: Oxidoreductase]]
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Current revision

1-deoxy-D-xylulose 5-phosphate reductoisomerase from Vibrio vulnificus in complex with Mn(2+)

PDB ID 5krr

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