User:Luis Andres Casavilca Ramirez/Sandbox 1
From Proteopedia
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== Structure == | == Structure == | ||
| - | Though the overall conserved bilobed shape of many Class 2 effectors consisting of a recognition and nuclease lobe is present,(2,3) Cas13b has a unique domain organization even among Cas13s. (Fig.1). A crystal structure of PbuCas13b complexed with a 36-nt direct repeat sequence and a 5-nt spacer at 1.65 Å provides information of the <scene name='81/817991/Pbucas13b_domains/2'>domains’ three dimensional arrange</scene>. There are five domains within the effector structure: two HEPN domains (<scene name='81/817991/Hepn1_and_hepn2/1'>HEPN1 and HEPN2</scene>), | + | Though the overall conserved bilobed shape of many Class 2 effectors consisting of a recognition and nuclease lobe is present,(2,3) Cas13b has a unique domain organization even among Cas13s. (Fig.1). A crystal structure of PbuCas13b complexed with a 36-nt direct repeat sequence and a 5-nt spacer at 1.65 Å provides information of the <scene name='81/817991/Pbucas13b_domains/2'>domains’ three dimensional arrange</scene>. There are five domains within the effector structure: two HEPN domains (<scene name='81/817991/Hepn1_and_hepn2/1'>HEPN1 and HEPN2</scene>), |
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== cnRNA and Targeting == | == cnRNA and Targeting == | ||
Revision as of 14:46, 14 June 2019
==Introduction==
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