DnaJ homolog

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</StructureSection>
</StructureSection>
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==3D structures of DnaJ homolog==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*DnaJ homolog subfamily A member 1
 
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**[[2lo1]], [[2m6y]] - hDnaJA1 J domain - human - NMR<br />
 
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*DnaJ homolog subfamily A member 3
 
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**[[2dn9]] - hDnaJA3 J domain - NMR<br />
 
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**[[2ctt]] - hDnaJ zinc finger domain - NMR<br />
 
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*DnaJ homolog subfamily B member 1
 
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**[[3agx]], [[2qld]] - hDnaJB1 peptide-binding domain <br />
 
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**[[3agy]], [[3agz]] - hDnaJB1 peptide-binding domain + HSP70 peptide<br />
 
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*DnaJ homolog subfamily B member 2
 
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**[[2lgw]] - hDnaJB2 J domain - NMR<br />
 
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*DnaJ homolog subfamily B member 8
 
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**[[2dmx]] - hDnaJB8 J domain - NMR<br />
 
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*DnaJ homolog subfamily B member 9
 
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**[[2ctr]] - hDnaJB9 J domain - NMR<br />
 
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*DnaJ homolog subfamily B member 12
 
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**[[2ctp]] - hDnaJB12 J domain - NMR<br />
 
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*DnaJ homolog subfamily C member 1
 
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**[[2cqq]], [[2cqr]] - hDnaJC1 DNA-binding domain - NMR<br />
 
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*DnaJ homolog subfamily C member 2
 
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**[[2m2e]] - hDnaJC2 SANT 2 domain residues 551-621 - NMR<br />
 
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**[[6cgh]] - hDnaJC2 residues 346-432- NMR<br />
 
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*DnaJ homolog subfamily C member 3
 
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**[[2y4t]], [[2y4u]] - hDnaJC3 residues 35-461 <br />
 
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**[[3ieg]] - mDnaJC3 TPR domain <br />
 
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*DnaJ homolog subfamily C member 5
 
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**[[2ctw]] - DnaJC5 J domain - mouse - NMR<br />
 
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**[[2n04]], [[2n05]] - hDnaJC5 N terminal domain - NMR<br />
 
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*DnaJ homolog subfamily C member 10
 
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**[[3apo]] - mDnaJC10 <br />
 
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**[[5ayk]], [[5ayl]] - mDnaJC10 (mutant)<br />
 
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**[[3aps]] - hDnaJC10 TRX4 domain <br />
 
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**[[3apq]] - mDnaJC10 TRX4 domain <br />
 
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*DnaJ homolog subfamily C member 12 see Hsp40 in [[Heat Shock Proteins]]
 
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*DnaJ homolog subfamily C member 17
 
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**[[2d9o]] - hDnaJC17 RNA recognition motif 168-254 - NMR<br />
 
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*DnaJ homolog subfamily C member 24
 
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**[[2l6l]] - hDnaJC24 - NMR<br />
 
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*DnaJ homolog subfamily C member 29 or sacsin. Domains: UBL 2-85; SR1 89-336; HEPN 4440-4579
 
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**[[5v44]] - hDnaJC29 Sr1 domain <br />
 
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**[[5v45]], [[5v46]] - hDnaJC29 Sr1 domain (mutant)<br />
 
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**[[5vsx]] - hDnaJC29 UBL domain<br />
 
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**[[5vsz]] - hDnaJC29 UBL domain (mutant)<br />
 
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**[[3o10]] - hDnaJC29 HEPN domain <br />
 
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*DnaJ homolog DnJ-2
 
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**[[2qsa]] - DnaJ-2 J domain - ''Caenorhabditis elegans''<br />
 
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}}
 
== References ==
== References ==

Revision as of 10:22, 16 June 2019

Human DnaJ homolog subfamity B member 1 peptide-binding domain dimer (cyan and green) complex with 3 C-terminal peptides of heat shock protein 70 (pink, magenta, violet) (PDB code 3agy)

Drag the structure with the mouse to rotate

References

  1. Terada K, Mori M. Human DnaJ homologs dj2 and dj3, and bag-1 are positive cochaperones of hsc70. J Biol Chem. 2000 Aug 11;275(32):24728-34. PMID:10816573 doi:http://dx.doi.org/10.1074/jbc.M002021200
  2. Rauch JN, Gestwicki JE. Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro. J Biol Chem. 2014 Jan 17;289(3):1402-14. doi: 10.1074/jbc.M113.521997. Epub 2013 , Dec 5. PMID:24318877 doi:http://dx.doi.org/10.1074/jbc.M113.521997
  3. Stark JL, Mehla K, Chaika N, Acton TB, Xiao R, Singh PK, Montelione GT, Powers R. Structure and function of human DnaJ homologue subfamily a member 1 (DNAJA1) and its relationship to pancreatic cancer. Biochemistry. 2014 Mar 4;53(8):1360-72. doi: 10.1021/bi401329a. Epub 2014 Feb 19. PMID:24512202 doi:http://dx.doi.org/10.1021/bi401329a
  4. Suzuki H, Noguchi S, Arakawa H, Tokida T, Hashimoto M, Satow Y. Peptide-binding sites as revealed by the crystal structures of the human Hsp40 Hdj1 C-terminal domain in complex with the octapeptide from human Hsp70. Biochemistry. 2010 Oct 5;49(39):8577-84. Epub 2010 Sep 9. PMID:20809635 doi:10.1021/bi100876n

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