This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6drs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:13, 11 October 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='6drs' size='340' side='right'caption='[[6drs]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6drs' size='340' side='right'caption='[[6drs]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6drs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DRS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6drs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_flavus_NRRL3357 Aspergillus flavus NRRL3357]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DRS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H8A:3-{[(3R)-7,9-diamino-3-methyl-2,3-dihydrofuro[2,3-f]quinazolin-4-yl]oxy}benzonitrile'>H8A</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.997&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6drs OCA], [http://pdbe.org/6drs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6drs RCSB], [http://www.ebi.ac.uk/pdbsum/6drs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6drs ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=H8A:3-{[(3R)-7,9-diamino-3-methyl-2,3-dihydrofuro[2,3-f]quinazolin-4-yl]oxy}benzonitrile'>H8A</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6drs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6drs OCA], [https://pdbe.org/6drs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6drs RCSB], [https://www.ebi.ac.uk/pdbsum/6drs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6drs ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/B8NBN5_ASPFN B8NBN5_ASPFN]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
 +
[[Category: Aspergillus flavus NRRL3357]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Akers-Rodriguez, S]]
+
[[Category: Akers-Rodriguez S]]
-
[[Category: Bensen, D C]]
+
[[Category: Bensen DC]]
-
[[Category: Fortier, J M]]
+
[[Category: Fortier JM]]
-
[[Category: Tari, L W]]
+
[[Category: Tari LW]]
-
[[Category: Antifolate]]
+
-
[[Category: Antifungal protein]]
+
-
[[Category: Antifungal protein-inhibitor complex]]
+
-
[[Category: Dhfr]]
+

Current revision

Dihydrofolate Reductase (DHFR) of Aspergillus flavus in complex with a small molecule inhibitor

PDB ID 6drs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools