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4yzm

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<StructureSection load='4yzm' size='340' side='right'caption='[[4yzm]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='4yzm' size='340' side='right'caption='[[4yzm]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4yzm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Dicdi Dicdi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YZM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YZM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4yzm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YZM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YZM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4K4:2-[(2-METHOXY-4-{[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]CARBONYL}PHENYL)AMINO]-5,11-DIMETHYL-5,11-DIHYDRO-6H-PYRIMIDO[4,5-B][1,4]BENZODIAZEPIN-6-ONE'>4K4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4K4:2-[(2-METHOXY-4-{[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]CARBONYL}PHENYL)AMINO]-5,11-DIMETHYL-5,11-DIHYDRO-6H-PYRIMIDO[4,5-B][1,4]BENZODIAZEPIN-6-ONE'>4K4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">roco4, DDB_G0288251 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 DICDI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yzm OCA], [https://pdbe.org/4yzm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yzm RCSB], [https://www.ebi.ac.uk/pdbsum/4yzm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yzm ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yzm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yzm OCA], [http://pdbe.org/4yzm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yzm RCSB], [http://www.ebi.ac.uk/pdbsum/4yzm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yzm ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ROCO4_DICDI ROCO4_DICDI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4yzm" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4yzm" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Dicdi]]
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[[Category: Dictyostelium discoideum]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: Alessi DR]]
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[[Category: Alessi, D R]]
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[[Category: Gilsbach BK]]
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[[Category: Gilsbach, B K]]
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[[Category: Ito G]]
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[[Category: Ito, G]]
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[[Category: Kortholt A]]
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[[Category: Kortholt, A]]
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[[Category: Messias AC]]
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[[Category: Messias, A C]]
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[[Category: Sattler M]]
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[[Category: Sattler, M]]
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[[Category: Wittinghofer A]]
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[[Category: Wittinghofer, A]]
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[[Category: Inhibitor]]
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[[Category: Kinase]]
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[[Category: Lrrk2]]
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[[Category: Roco-protein]]
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[[Category: Transferase]]
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Revision as of 07:32, 10 May 2023

Humanized Roco4 bound to LRRK2-In1

PDB ID 4yzm

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