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4zbp

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<StructureSection load='4zbp' size='340' side='right'caption='[[4zbp]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='4zbp' size='340' side='right'caption='[[4zbp]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4zbp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZBP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZBP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4zbp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZBP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADV:ALPHA-BETA+METHYLENE+ADP-RIBOSE'>ADV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADV:ALPHA-BETA+METHYLENE+ADP-RIBOSE'>ADV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zb3|4zb3]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zbp OCA], [https://pdbe.org/4zbp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zbp RCSB], [https://www.ebi.ac.uk/pdbsum/4zbp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zbp ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NUDT7, GFG1, NUDX7, At4g12720, T20K18.70 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zbp OCA], [http://pdbe.org/4zbp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zbp RCSB], [http://www.ebi.ac.uk/pdbsum/4zbp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zbp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NUDT7_ARATH NUDT7_ARATH]] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8-oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling.<ref>PMID:15878881</ref> <ref>PMID:16154395</ref> <ref>PMID:16328543</ref> <ref>PMID:16531493</ref> <ref>PMID:17660350</ref>
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[https://www.uniprot.org/uniprot/NUDT7_ARATH NUDT7_ARATH] Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can use both NADH and ADP-ribose as substrates, but not 8-oxo-dGTP, cyclic ADP-ribose, GDP-manose, UDP-glucose, ATP, or GTP. Exerts negative control of EDS1 signaling.<ref>PMID:15878881</ref> <ref>PMID:16154395</ref> <ref>PMID:16328543</ref> <ref>PMID:16531493</ref> <ref>PMID:17660350</ref>
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==See Also==
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*[[Nudix hydrolase 3D structures|Nudix hydrolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arath]]
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[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ding, J]]
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[[Category: Ding J]]
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[[Category: Liu, C]]
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[[Category: Liu C]]
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[[Category: Tang, Q]]
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[[Category: Tang Q]]
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[[Category: Zhong, C]]
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[[Category: Zhong C]]
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[[Category: Ampcpr]]
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[[Category: Closed conformation]]
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[[Category: Hydrolase]]
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[[Category: Nudix]]
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Revision as of 07:48, 10 May 2023

Crystal structure of the AMPCPR-bound AtNUDT7

PDB ID 4zbp

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