Endonuclease
From Proteopedia
(Difference between revisions)
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</StructureSection> | </StructureSection> | ||
| - | ==3D structures of endonuclease== | ||
| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
| - | |||
| - | *ENN-I | ||
| - | |||
| - | **[[1bix]] - hENN – human<br /> | ||
| - | **[[5um9]], [[5kse]], [[5k97]] – hENN (mutant) + DNA <br /> | ||
| - | **[[1cfr]] – ENN – ''Citrobacter freundii''<br /> | ||
| - | **[[1af5]] - CrENN – ''Chlamydomonas reinhardtii''<br /> | ||
| - | **[[1fzr]], [[1m0d]], [[1m0i]], [[3cae]] – T7ENN - Enterobacteria phage T7<br /> | ||
| - | **[[2g7e]], [[2g7f]] – VcENN – ''Vibrio cholera''<br /> | ||
| - | **[[2vnd]] - VcENN (mutant) <br /> | ||
| - | **[[2pu3]] - VsENN – ''Vibrio salmonicida'' | ||
| - | |||
| - | *ENN-II | ||
| - | |||
| - | **[[1pvi]], [[1pvu]] - ENN – ''Proteus vulgaris''<br /> | ||
| - | **[[2wsh]] - T4ENN (mutant) - Enterobacteria phage T4<br /> | ||
| - | **[[3w52]], [[4cwm]], [[4cxo]], [[4cxp]], [[4cxv]] – ENN – ''Arabidopsis thaliana''<br /> | ||
| - | |||
| - | *ENN-III | ||
| - | |||
| - | **[[2abk]], [[1ako]] - EcENN – ''Escherichia coli''<br /> | ||
| - | **[[1orn]], [[1orp]], [[1p59]] - GsENN + DNA – ''Geobacillus stearothermophilus''<br /> | ||
| - | **[[4unf]] – DrENN-1 – ''Deinococcus radiodurans'' <br /> | ||
| - | **[[4uob]] – DrENN-3 <br /> | ||
| - | |||
| - | *ENN-IV | ||
| - | |||
| - | **[[1qtw]] - EcENN <br /> | ||
| - | **[[2nqh]] - EcENN (mutant) <br /> | ||
| - | **[[1qum]] – EcENN + DNA<br /> | ||
| - | **[[2nqj]], [[2nq9]], [[4k1g]] - EcENN (mutant) + DNA<br /> | ||
| - | **[[1xp3]] - ENN – ''Bacillus anthracis''<br /> | ||
| - | **[[3aal]] - GkENN – ''Geobacillus kaustophilus''<br /> | ||
| - | **[[3aam]] - TtENN – ''Thermus thermophilus'' | ||
| - | |||
| - | *ENN-V | ||
| - | |||
| - | **[[4nsp]] – hENN catalytic domain<br /> | ||
| - | **[[1eni]], [[1enj]], [[1enk]], [[2end]] - T4ENN <br /> | ||
| - | **[[1vas]] - T4ENN + DNA<br /> | ||
| - | **[[2w35]], [[2w36]], [[4b20]] - TmENN + DNA – ''Thermotoga maritima''<br /> | ||
| - | **[[3hd0]] - TmENN <br /> | ||
| - | **[[3ga2]] - BsENN (mutant) – ''Bacillus subtilis''<br /> | ||
| - | **[[3goc]] - ENN – ''Streptomyces avermitilis''<br /> | ||
| - | **[[2fcc]] – T4ENN + DNA<br /> | ||
| - | |||
| - | *ENN-VII | ||
| - | |||
| - | **[[1en7]], [[1e7d]] - T4ENN <br /> | ||
| - | **[[1e7l]] - T4ENN (mutant) <br /> | ||
| - | **[[2qnc]], [[2qnf]] - T4ENN (mutant) + DNA | ||
| - | |||
| - | *ENN-VIII | ||
| - | |||
| - | **[[1tdh]] – hENN <br /> | ||
| - | **[[1bix]] – hENN + DNA<br /> | ||
| - | **[[1q39]], [[1q39]] - EcENN <br /> | ||
| - | **[[1q3b]], [[1q3c]] - EcENN (mutant) <br /> | ||
| - | **[[1k3x]], [[2ea0]], [[1k3w]], [[1k3x]], [[2ea0]], [[2opf]], [[2oq4]] - EcENN + DNA <br /> | ||
| - | **[[2opf]], [[2oq4]], [[6fbu]] - EcENN (mutant) + DNA | ||
| - | |||
| - | *AP ENN | ||
| - | |||
| - | **[[3ngf]] - ENN - ''Brucella melitensis''<br /> | ||
| - | **[[2j63]] – ENN – ''Leishmania major''<br /> | ||
| - | |||
| - | *Cas ENN | ||
| - | |||
| - | **[[1wj9]], [[4ej3]] – TtCas<br /> | ||
| - | **[[4n06]] – AfCas1 - ''Archaeoglobus fulgidus'' <br /> | ||
| - | **[[3god]] – PaCas1 – ''Pseudomonas aeruginosa''<br /> | ||
| - | **[[3nkd]] – EcCas1<br /> | ||
| - | **[[4wj0]] – PhCas1 - ''Pyrococcus horikoshii''<br /> | ||
| - | **[[4xtk]] – TmCas1<br /> | ||
| - | **[[5fcl]] – Cas1 - ''Pectobacterium atrosepticum''<br /> | ||
| - | **[[4zkj]] - SpCas1 – ''Streptococcus pyogenes''<br /> | ||
| - | **[[3oq2]] – Cas2 – ''Desulfovibrio vulgaris''<br /> | ||
| - | **[[4mak]] – EcCas2<br /> | ||
| - | **[[4p6i]], [[4qdl]] – EcCas1 + EcCas2<br /> | ||
| - | **[[6qy3]] – GsCas1 + EcCas2 + Csn2 – Cryo EM<br /> | ||
| - | **[[3s4l]] – MjCas3 – ''Methanocaldococcus jannaschii''<br /> | ||
| - | **[[4qqw]] – TfCas3 – ''Thermobifida fusca''<br /> | ||
| - | **[[4qqx]] – TfCas3 + ATP <br /> | ||
| - | **[[4qqy]] – TfCas3 + ADP <br /> | ||
| - | **[[4qqz]] – TfCas3 + AMPPNP <br /> | ||
| - | **[[4q2c]] - TteCas3 – ''Thermobaclum terrenum''<br /> | ||
| - | **[[4q2d]] - TteCas3 + ATP<br /> | ||
| - | **[[3i4h]] – Cas4 - ''Pyrobaculum calidifontis''<br / | ||
| - | **[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br /> | ||
| - | **[[4ilr]], [[3zfv]] – SsCas6 <br /> | ||
| - | **[[3i4h]] – PfCas6 - ''Pyrococcus furiosus''<br /> | ||
| - | **[[4dzd]] – EcCas6e<br /> | ||
| - | **[[4qr0]], [[4qr1]] - SpCas9 (Csn1) – ''Streptococcus pyogenes''<br /> | ||
| - | **[[4qr0]], [[4qr1]], [[4cmp]], [[4cmq]] - SpCas9 <br /> | ||
| - | **[[4ogc]], [[4oge]] – Cas9 II-C – ''Actinomyces naeslundii''<br /> | ||
| - | **[[3ung]], [[3ur3]], [[4doz]], [[4w8y]] – PfCas10 CMR2 subunit <br /> | ||
| - | **[[4h4k]] – PfCas10 CMR2+CMR3 subunits <br /> | ||
| - | **[[3w2v]] – PfCas10 CMR2+CMR3 subunits + AMP<br /> | ||
| - | **[[3w2w]] – PfCas10 CMR2+CMR3 subunits + ATP<br /> | ||
| - | **[[4gkf]] – PfCas10 CMR5 subunit<br /> | ||
| - | **[[4an8]], [[4f3e]] – TtCasA (Cse1)<br /> | ||
| - | **[[4h3t]] - CasA (Cse1) – ''Acidimicrobium ferrooxidans''<br /> | ||
| - | **[[4h79]] - TfCasB (Cse2)<br /> | ||
| - | **[[3wa8]] - CasB (Cse2) – ''Meiothermus ruber''<br /> | ||
| - | **[[4h7a]] - TtCasB (Cse2)<br /> | ||
| - | **[[4tvx]] – EcCasA (Cse1) + CasE<br /> | ||
| - | **[[3qhq]] - Csn2 – ''Streptococcus agalactiae''<br /> | ||
| - | **[[3toc]], [[3v7f]] – SpCsn2<br /> | ||
| - | **[[3ps0]] – SsCsa2<br /> | ||
| - | |||
| - | *Cas ENN complex with RNA and DNA | ||
| - | |||
| - | **[[5dlj]], [[5dqt]], [[5dqu]], [[5dqz]], [[5ds4]], [[5ds5]], [[5ds6]], [[5vvl]], [[5vvk]], [[5vvj]] – EcCas1 + EcCas2 + DNA<br /> | ||
| - | **[[5wfe]] – EcCas1 + EcCas2 + IHF-a + IHF-b + DNA<br /> | ||
| - | **[[5xvp]], [[5xvo]], [[5xvn]] – Cas1 + Cas2 + DNA – ''Enterococcus faecalis''<br /> | ||
| - | **[[6qxt]], [[6qxf]] – GsCas1 (mutant) + EcCas2 + Csn2 + DNA – Cryo EM<br /> | ||
| - | **[[4ill]], [[4ilm]] – SsCas6 + RNA - ''Sulfolobus solfataricus''<br /> | ||
| - | **[[5uz9]] – PaCsa5f + Cas7f + Cas8f + anti-crispr protein + RNA - Cryo EM<br /> | ||
| - | **[[6b48]], [[6b47]], [[6b46]], [[6b45]] – PaCsa6 + Csy1 + Csy2 + Csy3 + anti-crispr protein + RNA - Cryo EM<br /> | ||
| - | **[[6b44]] – PaCsa6 + Csy1 + Csy2 + Csy3 + anti-crispr protein + DNA - Cryo EM<br /> | ||
| - | **[[6ne0]] – PaCsa6/Csy4 + Csy1 + Csy2 + Csy3 + DNA + RNA – Cryo EM<br /> | ||
| - | **[[3pkm]] – PfCas6 + RNA<br /> | ||
| - | **[[2y8w]], [[2y8y]], [[3qrp]], [[3qrq]], [[2qrr]] – TtCas6e (Cse3) + RNA<br /> | ||
| - | **[[2xli]], [[2xlj]], [[2xlk]], [[4al7]] – PaCas6f (Csy4) + RNA <br /> | ||
| - | **[[4al5]], [[4al6]] - PaCas6f (Csy4) (mutant) + RNA <br /> | ||
| - | **[[4zt0]] - SpCas9 + RNA <br /> | ||
| - | **[[4zt9]] - SpCas9 (mutant) + RNA <br /> | ||
| - | **[[5f9r]] - SpCas9 + RNA + DNA<br /> | ||
| - | **[[4oo8]], [[4un3]], [[4un4]], [[4un5]], [[5fw1]], [[5fw2]], [[5fw3]], [[5fq5]], [[5b2r]], [[5b2s]], [[5b2t]], [[5y36]], [[6ia6]] - SpCas9 (Csn1) (mutant) + RNA + DNA<br /> | ||
| - | **[[5xbl]] - SpCas9 + associated protein + RNA <br /> | ||
| - | **[[6ifo]] - SpCas9 + AcriiA2 + RNA <br /> | ||
| - | **[[5vw1]] - SpCas9 + AcriiA4 + RNA <br /> | ||
| - | **[[6mcc]], [[5vzl]], [[6mcb]] - SpCas9 + AcriiA4 + RNA – Cryo EM<br /> | ||
| - | **[[5vgb]] - NmCas9 + AcriiC1 – Neisseria meningitidis <br /> | ||
| - | **[[6jdx]], [[6jdj], [[6j9m]]] - NmCas9 + AcriiC2 <br /> | ||
| - | **[[6j9n]] - NmCas9 + AcriiC3 <br /> | ||
| - | **[[5x2h]], [[5x2g]] – Cas9 + RNA + DNA – ''Campylobacter jejuni''<br /> | ||
| - | **[[5czz]] - SaCas9 (Csn1) + RNA + DNA - ''Staphylococcus aureus''<br /> | ||
| - | **[[5axw]] - SaCas9 (Csn1) (mutant) + RNA + DNA <br /> | ||
| - | **[[6joo]] - Cas9 + RNA + DNA – Corynebacterium diphtheriae<br /> | ||
| - | **[[5b2o]], [[5b2p]], [[5b2q]] - FtCas9 (mutant) + RNA + DNA – ''Francisella tularensis''<br /> | ||
| - | **[[6i1l]], [[6i1k]], [[6gtg]], [[6gtf]], [[6gte]], [[6gtd]], [[6gtc]] – FtCas12a (mutant) + RNA + DNA <br /> | ||
| - | **[[4u7u]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA<br /> | ||
| - | **[[4qyz]], [[5h9f]], [[5h9e]] – EcCasA (Cse1) + CasB + CasC + CasD + CasE + RNA + DNA<br /> | ||
| - | **[[5wqe]] – AaCas C2C1 + RNA – ''Alicyclobacillus acidoterrestris''<br /> | ||
| - | **[[5u34]] – AaCas C2C1 (mutant) + RNA <br /> | ||
| - | **[[5u30]], [[5u31]], [[5u33]] – AaCas C2C1 + RNA + DNA<br /> | ||
| - | **[[5kk5]], [[5b43]] – AcCas Cpf1 + RNA + DNA – ''Acidaminococcus''<br /> | ||
| - | **[[5xh7]], [[5xh6]] – AcCas Cpf1 (mutant) + RNA + DNA <br /> | ||
| - | **[[5ng6]] – FtCas Cpf1 + RNA <br /> | ||
| - | **[[5nfv]], [[5mga]] – FtCas Cpf1 + RNA + DNA <br /> | ||
| - | |||
| - | *EcoKI ENN | ||
| - | |||
| - | **[[2ar0]] – EcENN (mutant)<br /> | ||
| - | |||
| - | *Ecoo109I ENN | ||
| - | |||
| - | **[[1wtd]] - EcENN<br /> | ||
| - | **[[1wte]] – EcENN + DNA<br /> | ||
| - | |||
| - | *EcoRI ENN | ||
| - | |||
| - | **[[1qc9]] - EcENN<br /> | ||
| - | **[[1eri]], [[1ckq]], [[1cl8]], [[1qps]] – EcENN + DNA<br /> | ||
| - | **[[1qrh]], [[1qri]], [[2oxv]] - EcENN (mutant) + DNA | ||
| - | |||
| - | *EcoRII ENN | ||
| - | |||
| - | **[[1na6]] – EcENN<br /> | ||
| - | **[[3hqf]], [[3hqg]] - EnENN + DNA | ||
| - | |||
| - | *EcoRV ENN | ||
| - | |||
| - | **[[1rve]], [[1az3]] – EcENN<br /> | ||
| - | **[[1az4]] - EcENN (mutant) <br /> | ||
| - | **[[2rve]], [[4rve]], [[1rva]], [[1rvb]], [[1rvc]], [[1az0]], [[1bsu]], [[1bua]], [[1bgb]], [[1rv5]], [[1b94]], [[1b95]], [[1eo3]], [[1eo4]], [[1eon]], [[1eoo]], [[1eop]], [[2b0d]], [[2b0e]], [[5hlk]] - EcENN + DNA<br /> | ||
| - | **[[1bss]], [[1b96]], [[1b97]], [[1stx]], [[1suz]], [[1sx5]], [[1sx8]], [[2ge5]] - EcENN (mutant) + DNA<br /> | ||
| - | **[[5f8a]] - EcENN + DNA + Lu<br /> | ||
| - | |||
| - | *BamHI ENN | ||
| - | |||
| - | **[[1bam]] – BaENN – ''Bacillus amyloliquefaciens''<br /> | ||
| - | **[[1bhm]], [[3bam]], [[2bam]], [[1esg]] - BaENN + DNA | ||
| - | |||
| - | *Bbvci ENN | ||
| - | |||
| - | **[[6mag]], [[6m9g]], [[6eg7]] – BbENN subunit 2 – ''Brevibacillus brevis''<br /> | ||
| - | **[[6maf]] – BbENN subunits 1+2 <br /> | ||
| - | |||
| - | *FokI ENN | ||
| - | |||
| - | **[[1fok]] – PoENN + DNA – ''Planomicrobium okeanokoites''<br /> | ||
| - | **[[2fok]] – PoENN | ||
| - | |||
| - | *LAGLIDAD ENN | ||
| - | |||
| - | **[[4z1x]] – fyENN + DNA – fission yeast<br /> | ||
| - | **[[5e5o]] – ENN + DNA – ''Sordaria macropora''<br /> | ||
| - | |||
| - | *PvuII ENN | ||
| - | |||
| - | **[[3pvi]] - PvENN (mutant) + DNA – ''Proteus vulgaris''<br /> | ||
| - | **[[1k0z]], [[1h56]], [[3ksk]] - PvENN<br /> | ||
| - | **[[1ni0]] - PvENN (mutant) <br /> | ||
| - | **[[2pvi]], [[1eyu]], [[1f0o]] - PvENN + DNA | ||
| - | |||
| - | *tRNA-splicing ENN | ||
| - | |||
| - | **[[2gw6]] – hENN subunit sen15 – NMR<br /> | ||
| - | **[[1a79]], [[1a76]], [[1a77]] - MjENN – ''Methanocaldococcus jannaschii''<br /> | ||
| - | **[[2cv8]] - ENN – ''Sulfolobus tokodaii''<br /> | ||
| - | **[[2gjw]] - AfENN + RNA –'' Archaeoglobus fulgidus''<br /> | ||
| - | **[[1r0v]], [[1r11]] – AfENN | ||
| - | **[[2ohc]], [[2ohe]] - TaENN – ''Thermoplasma acidophilum''<br /> | ||
| - | **[[2zyz]] – ENN – ''Pyrobaculum aerophilum''<br /> | ||
| - | **[[3iey]] - ENN + NEQ261 – ''Nanoarchaeum equitans''<br /> | ||
| - | **[[3ajv]] - ApENN (mutant) – ''Aeropyrum pernix''<br /> | ||
| - | **[[3p1y]] - ApENN /AfENN<br /> | ||
| - | **[[3p1z]] - ApENN + protein | ||
| - | |||
| - | *VSR ENN | ||
| - | |||
| - | **[[1vsr]] – EcENN<br /> | ||
| - | **[[1cw0]] - EcENN + DNA | ||
| - | |||
| - | *BglI ENN | ||
| - | |||
| - | **[[1dmu]], [[1d2i]] – BsENN + DNA <br /> | ||
| - | **[[1dfm]] - BsENN (mutant) + DNA | ||
| - | |||
| - | *BglII ENN | ||
| - | |||
| - | **[[1es8]] - BsENN | ||
| - | |||
| - | *MunI ENN | ||
| - | |||
| - | **[[1d02]] - ENN (mutant) + DNA - ''Mycoplasma'' | ||
| - | |||
| - | *Sm ENN | ||
| - | |||
| - | **[[1smn]], [[1qae]], [[1ql0]], [[1g8t]] – ENN – ''Serratia marcescens'' | ||
| - | |||
| - | *NaeI ENN | ||
| - | |||
| - | **[[1ev7]] - LaENN – ''Lechevalieria aerocolonigenes''<br /> | ||
| - | **[[1iaw]] - LaENN + DNA | ||
| - | |||
| - | *NgoMIV ENN | ||
| - | |||
| - | **[[1fiu]], [[4abt]] - ENN + DNA – ''Neisseria gonorrheae'' | ||
| - | |||
| - | *NEI ENN | ||
| - | |||
| - | **[[1tdh]] - hENN | ||
| - | |||
| - | *BsoBI ENN | ||
| - | |||
| - | **[[1dc1]] - GsENN + DNA | ||
| - | |||
| - | *Bse634I ENN | ||
| - | |||
| - | **[[1knv]] – GsENN<br /> | ||
| - | **[[3v1z]] – GsENN + DNA<br /> | ||
| - | **[[3v20]], [[3v21]] - GsENN (mutant) + DNA | ||
| - | |||
| - | *HincII ENN | ||
| - | |||
| - | **[[1kc6]], [[1tw8]], [[1xhu]], [[1xhv]], [[1tx3]], [[2gie]] - HiENN + DNA – ''Haemophilus influenza''<br /> | ||
| - | **[[2gig]], [[2gih]], [[2gii]], [[2gij]], [[3e3y]], [[3e40]], [[3e41]], [[3e42]], [[3e43]], [[3e44]], [[3e45]], [[3ebc]] - HiENN (mutant) + DNA<br /> | ||
| - | **[[2aud]] – HiENN | ||
| - | |||
| - | *HinDIII ENN | ||
| - | |||
| - | **[[2e52]], [[3a4k]] - HiENN + DNA | ||
| - | |||
| - | *HinP1I ENN | ||
| - | |||
| - | **[[1ynm]] – HiENN<br /> | ||
| - | **[[2fkc]], [[2fkh]], [[2fl3]], [[2flc]] - HiENN + DNA | ||
| - | |||
| - | *Flap ENN | ||
| - | |||
| - | **[[5zod]] - hENN <br /> | ||
| - | **[[3q8k]], [[3q8l]], [[3q8m]] - hENN + DNA<br /> | ||
| - | **[[5zog]], [[5zof]], [[5zoe]] - hENN (mutant) + DNA<br /> | ||
| - | **[[5fv7]] - hENN + inhibitor<br /> | ||
| - | **[[1ul1]] - hENN + PCNA <br /> | ||
| - | **[[1mc8]] - PhENN (mutant) <br /> | ||
| - | **[[3ory]]– ENN – ''Desulfurococcus amylolyticus''<br /> | ||
| - | **[[1rxv]], [[1rxw]] - AfENN + DNA<br /> | ||
| - | **[[2izo]] - SsENN + PCNA – ''Sulfolobus solfataricus''<br /> | ||
| - | **[[1a76]], [[1a77]] - MjENN <br /> | ||
| - | **[[1b43]] – PfENN – ''Pyrococcus furiosus''<br /> | ||
| - | **[[1rxz]] - AfENN + PCNA <br /> | ||
| - | **[[4wa8]] – ENN – ''Methanopyrus kandleri''<br /> | ||
| - | |||
| - | *DNA mismatch ENN | ||
| - | |||
| - | **[[1h7u]] – hENN<br /> | ||
| - | **[[6mfq]] – hENN Pms2<br /> | ||
| - | **[[5u5r]] – hENN + importin<br /> | ||
| - | **[[1odg]] - EcENN + DNA<br /> | ||
| - | |||
| - | *Vvn ENN | ||
| - | |||
| - | **[[1ouo]] – VvENN – ''Vibrio vulnificus''<br /> | ||
| - | **[[1oup]], [[2ivk]] - VvENN + DNA | ||
| - | |||
| - | *Structure-specific ENN | ||
| - | |||
| - | **[[4zou]] – hENN SLX4 subunit BTB domain<br /> | ||
| - | **[[4uyi]] – hENN SLX4 subunit BTB domain (mutant)<br /> | ||
| - | **[[4xm5]] – CgENN SLX1 subunit – ''Candida glabrata''<br /> | ||
| - | **[[4xlg]] – CgENN SLX1 (mutant)+SLX4 subunits<br /> | ||
| - | **[[4zdt]] – fyENN SLX1+SLX4 subunits<br /> | ||
| - | |||
| - | *BfiI ENN | ||
| - | |||
| - | **[[2c1l]] – ENN – ''Bacillus firmus'' | ||
| - | |||
| - | *SfiI ENN | ||
| - | |||
| - | **[[2ezv]], [[2f03]] – ENN + DNA – synthetic | ||
| - | |||
| - | *Ecl18kI ENN | ||
| - | |||
| - | **[[2fqz]], [[2gb7]] – ENN + DNA – ''Enterobacter cloacae'' | ||
| - | |||
| - | *SdaI ENN | ||
| - | |||
| - | **[[2ixs]] – ENN – ''Streptomyces diastaticus'' | ||
| - | |||
| - | *PabI ENN | ||
| - | |||
| - | **[[2dvy]] – ENN – ''Pyrococcus abyssi'' | ||
| - | |||
| - | *PspGI ENN | ||
| - | |||
| - | **[[3bm3]] – ENN – ''Pyrococcus'' | ||
| - | |||
| - | *HNH ENN | ||
| - | |||
| - | **[[4h6d]] – ENN – ''Geobacter metallireducens''<br /> | ||
| - | **[[5h0o]], [[5h0m]] – ENN – Geobacillus virus E2<br /> | ||
| - | **[[5cxr]] – ENN + pyrazole derivative – Influenza virus <br /> | ||
| - | **[[6j9l]]] - NmENN + AcriiC2 <br /> | ||
| - | |||
| - | *UV damage ENN | ||
| - | |||
| - | **[[2j6v]], [[3bzg]], [[3c0s]] – TtENN <br /> | ||
| - | **[[3bzj]], [[3c0l]], [[3c0q]] - TtENN (mutant)<br /> | ||
| - | **[[3tc3]] - SaENN <br /> | ||
| - | **[[4gle]] - SaENN + DNA<br /> | ||
| - | |||
| - | *NotI ENN | ||
| - | |||
| - | **[[3bvq]] - NoENN – ''Nocardia otitidiscaviarum''<br /> | ||
| - | **[[3c25]] - NoENN + DNA | ||
| - | |||
| - | *BpujI ENN | ||
| - | |||
| - | **[[2vla]], [[3s1s]] – BpENN – ''Bacillus pumilus''<br /> | ||
| - | **[[5hnf]], [[5hnh]], [[5hlt]] – BpENN + DNA <br /> | ||
| - | |||
| - | *Sau3AI ENN | ||
| - | |||
| - | **[[2reu]] – SaENN C terminal – ''Staphylococcus aureus''<br /> | ||
| - | **[[4pxg]] – SaENN (mutant) <br /> | ||
| - | |||
| - | *HpyI ENN | ||
| - | |||
| - | **[[3fc3]], [[3gox]] – HpENN99 + DNA – ''Helicobacter pylori''<br /> | ||
| - | **[[3or3]] – HpENN88 + DNA | ||
| - | |||
| - | *PacI ENN | ||
| - | |||
| - | **[[3ldy]], [[3m7k]] - PaENN + DNA – ''Psdeudomonas alcaligenes'' | ||
| - | |||
| - | *Crossover junction ENN | ||
| - | |||
| - | **[[2ziw]], [[2zix]], [[2ziu]] – hENN EME1 + Mus81<br /> | ||
| - | **[[2ziv]] – hENN EME1 (mutant) + Mus81<br /> | ||
| - | **[[4p0p]], [[4p0q]], [[4p0r]], [[4p0s]] – hENN EME1 + Mus81 + DNA<br /> | ||
| - | **[[2kpf]] - mENN – mouse<br /> | ||
| - | |||
| - | *OkrAI ENN | ||
| - | |||
| - | **[[3odh]] - ENN + DNA – ''Oceanobacter kriegii'' | ||
| - | |||
| - | *BspD6I ENN | ||
| - | |||
| - | **[[2ewf]] - ENN – ''Bacillus'' | ||
| - | |||
| - | *ThaI ENN | ||
| - | |||
| - | **[[3ndh]] - TaENN + DNA | ||
| - | |||
| - | *Xpf ENN | ||
| - | |||
| - | **[[1z00]], [[2a1j]] - hENN C terminal + DNA excision repair protein<br /> | ||
| - | **[[2aq0]] – hENN residues 823-905 – NMR<br /> | ||
| - | **[[2kn7]] – hENN residues 823-905 + DNA – NMR<br /> | ||
| - | **[[2bgw]] - ApENN + DNA <br /> | ||
| - | **[[2bhn]] - ApENN <br /> | ||
| - | |||
| - | *Mazf3 ENN | ||
| - | |||
| - | **[[5uct]], [[5cca]] - MtENN – ''Mycobacterium tuberculosis''<br /> | ||
| - | |||
| - | *Vapc ENN | ||
| - | |||
| - | **[[5wzf]], [[5wz4]] – MtENN-20 <br /> | ||
| - | **[[5ed0]], [[5ecy]] – SfENN – ''Shigella flexneri''<br /> | ||
| - | **[[5ecy]], [[5ecw]], [[5ecd]] – SfENN (mutant)<br /> | ||
| - | |||
| - | *Muts2 ENN | ||
| - | |||
| - | **[[4och]], [[4od6]] - DrENN SMR domain<br /> | ||
| - | |||
| - | *Endoms ENN | ||
| - | |||
| - | **[[5gkj]] – TkENN (mutant) – ''Thermococcus kodakarensis''<br /> | ||
| - | **[[5gke]], [[5gkf]], [[5gkg]], [[5gkh]], [[5gki]] – TkENN (mutant) + DNA<br /> | ||
| - | |||
| - | *ENN G | ||
| - | |||
| - | **[[5gkc]], [[4qn0]] – CeENN (mutant) – ''Caenorhabdfitis elegans''<br /> | ||
| - | **[[5gkp]] – CeENN (mutant) + DNA <br /> | ||
| - | |||
| - | *ENN S | ||
| - | |||
| - | **[[5ybb]] – ENN + R-M system + DNA – ''Caldanaerobacter subterraneus'' <br /> | ||
| - | |||
| - | *ENN V | ||
| - | |||
| - | **[[5aoy]] – mENN (mutant) <br /> | ||
| - | **[[4xpu]] – EcENN <br /> | ||
| - | |||
| - | *Apurinic-apyrimidinic ENN | ||
| - | |||
| - | **[[5cfg]], [[6mk3]], [[6mkk]], [[6mkm]], [[6mko]] – hENN <br /> | ||
| - | **[[5dff]], [[5dfh]], [[5dfi]], [[5dfj]], [[5dg0]], [[5wn5]], [[5wn4]], [[5wn3]], [[5wn2]], [[5wn1]], [[5wn0]], [[6bos]] – hENN + DNA<br /> | ||
| - | **[[6bot]], [[6boq]], [[6bor]], [[6bou]], [[6bov]], [[6bow]] – hENN (mutant) + DNA<br /> | ||
| - | |||
| - | *'''Intron-encoded endonuclease''' | ||
| - | |||
| - | *I-PpoI ENN | ||
| - | |||
| - | **[[1a74]], [[1ipp]], [[1a73]], [[1cz0]] - PpENN + DNA – ''Physarum polycephalum''<br /> | ||
| - | **[[1cyq]], [[1evw]], [[2o6m]] - PpENN (mutant) + DNA<br /> | ||
| - | **[[1evx]] - PpENN | ||
| - | |||
| - | *I-CreI ENN | ||
| - | |||
| - | **[[1bp7]], [[1g9y]], [[1g9z]], [[1n3e]], [[1n3f]], [[2vbj]], [[2vbl]], [[2vbn]], [[2vbo]], [[4aqu]], [[4aqx]] - CrENN + DNA <br /> | ||
| - | **[[1u0c]], [[1u0d]], [[1t9i]], [[1t9j]], [[2i3p]], [[2i3q]], [[4aab]], [[4aad]], [[4aae]], [[4aaf]], [[4aag]], [[6fb9]], [[6fb8]], [[6fb7]], [[6fb6]], [[6fb5]], [[6fb2]], [[6fb1]], [[6fb0]] - CrENN (mutant) + DNA<br /> | ||
| - | **[[2o7m]] - CrENN | ||
| - | |||
| - | *I-CeuI ENN | ||
| - | |||
| - | **[[2ex5]] - ENN (mutant) + DNA – ''Chlamydomonas eugametos'' | ||
| - | |||
| - | *I-DmoI ENN | ||
| - | |||
| - | **[[1b24]], [[2vs7]], [[2vs8]], [[4un7]], [[4un8]], [[4un9]], [[4una]], [[4unb]], [[4unc]], [[4ut0]], [[4d6n]], [[4d6o]], [[5ak9]], [[5a0w]], [[5o6g]], [[5o6i]] - DmENN + DNA – ''Desulfurococcus mobilis''<br /> | ||
| - | **[[5akf]], [[5akm]], [[5akn]] - DmENN (mutant) + DNA <br /> | ||
| - | **[[1mow]] – DmENN/CrENN + DNA | ||
| - | |||
| - | *I-AniI ENN | ||
| - | |||
| - | **[[1p8k]], [[2qoj]], [[3uvf]] - EnENN + DNA – ''Emericella nidulans''<br /> | ||
| - | **[[3eh8]] - EnENN (mutant) + DNA | ||
| - | |||
| - | *I-HmuI ENN | ||
| - | |||
| - | **[[1u3e]] - ENN + DNA – Bacillus phage spo1 | ||
| - | |||
| - | *I-TevI ENN | ||
| - | |||
| - | **[[1i3j]], [[1t2t]] - T4ENN + DNA<br /> | ||
| - | **[[1ln0]], [[1mk0]] – T4ENN (mutant) | ||
| - | |||
| - | *I-SceI ENN | ||
| - | |||
| - | **[[1dfa]], [[1ef0]] – yENN – yeast<br /> | ||
| - | **[[1gpp]] – yENN (mutant) <br /> | ||
| - | **[[1lws]], [[1lwt]], [[1r7m]], [[3c0w]], [[3c0x]], [[3ool]], [[5a0m]] - yENN + DNA<br /> | ||
| - | **[[3oor]] - yENN (mutant) + DNA | ||
| - | |||
| - | *I-PkoII ENN | ||
| - | |||
| - | **[[2cw7]], [[2cw8]] – TkENN | ||
| - | |||
| - | *I-MspI ENN | ||
| - | |||
| - | **[[1sa3]], [[1yfi]], [[2fld]] – ENN + DNA – ''Moraxella'' | ||
| - | |||
| - | *I-PfuI ENN | ||
| - | |||
| - | **[[1dq3]] – PfENN | ||
| - | |||
| - | *I-Tsp061I ENN | ||
| - | |||
| - | **[[2dch]] – ENN – ''Thermoproteus'' | ||
| - | |||
| - | *I-Vdi141I ENN | ||
| - | |||
| - | **[[3e54]] – ENN – ''Vulcanisaeta distribute'' | ||
| - | |||
| - | *I-MtuI ENN | ||
| - | |||
| - | **[[3ifj]], [[3igd]] - MtENN (mutant) <br /> | ||
| - | **[[2l8l]] - MtENN | ||
| - | |||
| - | *I-MsoI ENN | ||
| - | |||
| - | **[[1m5x]], [[3fd2]] – MoENN + DNA – ''Monomastix''<br /> | ||
| - | **[[3ko2]] – MoENN (mutant) + DNA | ||
| - | |||
| - | *I-GzeMII ENN | ||
| - | |||
| - | **[[4efj]] – ENN + DNA – ''Gibberella zeae'' | ||
| - | |||
| - | *I-tRNA ENN | ||
| - | |||
| - | **[[4fz2]] – ENN – ''Candidatus micrarchaeum''<br /> | ||
| - | |||
| - | *I-Cvui ENN | ||
| - | |||
| - | **[[5a78]], [[5a72]], [[5a74]], [[5a77]], [[5a78]] – ENN + DNA – ''Chlorella vulgaris''<br /> | ||
| - | |||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 07:25, 20 June 2019
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References
- ↑ Nishino T, Morikawa K. Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors. Oncogene. 2002 Dec 16;21(58):9022-32. PMID:12483517 doi:http://dx.doi.org/10.1038/sj.onc.1206135
- ↑ Horvath P, Barrangou R. CRISPR/Cas, the immune system of bacteria and archaea. Science. 2010 Jan 8;327(5962):167-70. doi: 10.1126/science.1179555. PMID:20056882 doi:http://dx.doi.org/10.1126/science.1179555
- ↑ Flick KE, Jurica MS, Monnat RJ Jr, Stoddard BL. DNA binding and cleavage by the nuclear intron-encoded homing endonuclease I-PpoI. Nature. 1998 Jul 2;394(6688):96-101. PMID:9665136 doi:10.1038/27952
