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Estrogen-related receptor

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</StructureSection>
</StructureSection>
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==3D structures of estrogen-related receptor==
 
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
 
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*ERR
 
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**[[1xb7]], [[3d24]] – hERR ligand-binding domain + peroxisome proliferator activated receptor coactivator 1 peptide – human<br />[[2pjl]] - hERR ligand-binding domain (mutant) + inverse agonist<br />
 
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**[[3k6p]] - hERR ligand-binding domain + ligand
 
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*ERRβ
 
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**[[1lo1]] – hERR DNA-binding domain + DNA - NMR
 
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*ERRγ
 
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**[[2gp7]], [[2zbs]] - hERR ligand-binding domain<br />
 
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**[[1kv6]], [[1tfc]] – hERR ligand-binding domain + steroid receptor coactivator 1 2nd NR-Box <br />
 
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**[[2gpo]], [[2gpp]] - hERR ligand-binding domain + nuclear receptor-interacting protein 1 peptide<br />
 
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**[[2ewp]] - hERR ligand-binding domain + tamoxifen analog<br />
 
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**[[2gpu]], [[2p7z]] - hERR ligand-binding domain + 4-hydroxytamoxifen<br />
 
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**[[2e2r]], [[2p7g]] - hERR ligand-binding domain + bisphenol A<br />
 
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**[[2zkc]] - hERR ligand-binding domain + bisphenol Z<br />
 
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**[[2zas]] - hERR ligand-binding domain + bisphenol A derivative<br />
 
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**[[6a6k]], [[5yso]] - hERR ligand-binding domain + piperazine derivative<br />
 
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**[[2p7a]] - hERR ligand-binding domain + methyl phenol<br />
 
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**[[2gpv]] - hERR ligand-binding domain + nuclear receptor corepressor 2 peptide + 4-hydroxytamoxifen<br />
 
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**[[1s9p]], [[1s9q]] - mERR ligand-binding domain + diethylstilbesterol – mouse<br />
 
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**[[1vjb]] - mERR ligand-binding domain + 4-hydroxytamoxifen<br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>

Revision as of 10:22, 23 June 2019

Human estrogen-related receptor γ ligand-binding domain (cyan, grey, green, yellow, pink, purple) complex with nuclear receptor corepressor 2 peptide (dark red, orange) and 4-hydroxytamoxifen (PDB code 2gpv)

Drag the structure with the mouse to rotate

References

  1. ↑ Ariazi EA, Jordan VC. Estrogen-related receptors as emerging targets in cancer and metabolic disorders. Curr Top Med Chem. 2006;6(3):203-15. PMID:16515477
  2. ↑ Wang L, Zuercher WJ, Consler TG, Lambert MH, Miller AB, Orband-Miller LA, McKee DD, Willson TM, Nolte RT. X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation. J Biol Chem. 2006 Dec 8;281(49):37773-81. Epub 2006 Sep 21. PMID:16990259 doi:http://dx.doi.org/10.1074/jbc.M608410200

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Wayne Decatur

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