6p08

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'''Unreleased structure'''
 
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The entry 6p08 is ON HOLD until Paper Publication
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==Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate==
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<StructureSection load='6p08' size='340' side='right'caption='[[6p08]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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Authors: Selvaraj, B., Cuneo, M.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6p08]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6P08 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6P08 FirstGlance]. <br>
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Description: Ternary structure of the E52D mutant of ANT-4'' with Neomycin, AMP and Pyrophosphate
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NMY:NEOMYCIN'>NMY</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6p08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6p08 OCA], [http://pdbe.org/6p08 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6p08 RCSB], [http://www.ebi.ac.uk/pdbsum/6p08 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6p08 ProSAT]</span></td></tr>
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[[Category: Cuneo, M.J]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/KANU_BACSP KANU_BACSP]] Inactivates the antibiotic kanamycin by catalyzing the transfer of a nucleotidyl group from nucleoside triphosphates such as ATP to the 4'-hydroxyl group of the aminoglycoside.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Cuneo, M J]]
[[Category: Selvaraj, B]]
[[Category: Selvaraj, B]]
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[[Category: Antibiotic]]
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[[Category: Dna polymerase]]
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[[Category: Transferase-antibiotic complex]]

Revision as of 15:33, 29 January 2020

Ternary structure of the E52D mutant of ANT-4 with Neomycin, AMP and Pyrophosphate

PDB ID 6p08

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