6s1r
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of fission yeast Mis16 bound to histone H4== | |
| - | + | <StructureSection load='6s1r' size='340' side='right'caption='[[6s1r]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6s1r]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S1R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6S1R FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6s1r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s1r OCA], [http://pdbe.org/6s1r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s1r RCSB], [http://www.ebi.ac.uk/pdbsum/6s1r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s1r ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/HAT2_SCHPO HAT2_SCHPO]] Regulatory subunit of the histone acetylase B (HAT-B) complex (By similarity). The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing (By similarity). Component of the CENP-A recruiting complex that ensures the integrity of mitotic spindles through maintenance of kinetochore factors mis6/CENP-I and cnp1/CENP-A (PubMed:15369671, PubMed:24774534, PubMed:24789708, PubMed:25375240). Maintains the deacetylated state of histones specifically in the central core of the centromeres (PubMed:15369671).[UniProtKB:P39984]<ref>PMID:15369671</ref> <ref>PMID:24774534</ref> <ref>PMID:24789708</ref> <ref>PMID:25375240</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Korntner-Vetter, M]] | ||
| + | [[Category: Lefevre, S]] | ||
| + | [[Category: Singleton, M R]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Centromere mitosis wd40 histone chaperone]] | ||
Revision as of 06:06, 7 August 2019
Structure of fission yeast Mis16 bound to histone H4
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