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6s20
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Metabolism of multiple glycosaminoglycans by bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus (BT3336S-sulf)== | |
| - | + | <StructureSection load='6s20' size='340' side='right'caption='[[6s20]], [[Resolution|resolution]] 1.98Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6s20]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6S20 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NG6:N-ACETYL-D-GALACTOSAMINE+6-SULFATE'>NG6</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6s20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s20 OCA], [http://pdbe.org/6s20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s20 RCSB], [http://www.ebi.ac.uk/pdbsum/6s20 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s20 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GALSF_BACTN GALSF_BACTN]] Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS) and dermatan sulfate (DS). Catalyzes the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units (PubMed:25002587). GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract (PubMed:25002587).<ref>PMID:25002587</ref> <ref>PMID:25002587</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Basle, A]] | ||
| + | [[Category: Cartmell, A]] | ||
| + | [[Category: Henrissat, B]] | ||
[[Category: Ndeh, D]] | [[Category: Ndeh, D]] | ||
| - | [[Category: Cartmell, A]] | ||
[[Category: Strahl, H]] | [[Category: Strahl, H]] | ||
| - | [[Category: Henrissat, B]] | ||
[[Category: Terrapon, N]] | [[Category: Terrapon, N]] | ||
| - | [[Category: | + | [[Category: Cazyme]] |
| + | [[Category: Glycobiology]] | ||
| + | [[Category: Glycosaminoglycan]] | ||
| + | [[Category: Gut microbiota]] | ||
| + | [[Category: Hydrolase]] | ||
Revision as of 08:08, 5 February 2020
Metabolism of multiple glycosaminoglycans by bacteroides thetaiotaomicron is orchestrated by a versatile core genetic locus (BT3336S-sulf)
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