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LDL receptor

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Line 29: Line 29:
**[[2lgp]] – hLDLR LB4,LB5 - NMR<br />
**[[2lgp]] – hLDLR LB4,LB5 - NMR<br />
**[[1xfe]] – hLDLR LB7,EGF - NMR<br />
**[[1xfe]] – hLDLR LB7,EGF - NMR<br />
-
**[[1yxj]], [[1yxk]] – hLDLR LBD LB4,LB5, LB6<br />
+
**[[1yxj]], [[1yxk]], [[6tl7]], [[6tla]] – hLDLR LBD LB4,LB5,LB6<br />
 +
**[[6tl9]] – hLDLR LBD LB4,LB5,LB6 + inhibitor<br />
*hLDLR ligand-binding domain complex with protein
*hLDLR ligand-binding domain complex with protein

Revision as of 09:16, 31 August 2020

Structure of human LDLR LBD and EGFP domains (magenta) complex with proprotein convertase subtilisin/kexin 9-CoA reductase (cyan and green) and Ca+2 ions (green) (PDB entry 3m0c)

Drag the structure with the mouse to rotate

3D structures of LDL receptor

Updated on 31-August-2020

References

  1. ↑ Goldstein JL, Brown MS. The LDL receptor. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):431-8. doi:, 10.1161/ATVBAHA.108.179564. PMID:19299327 doi:http://dx.doi.org/10.1161/ATVBAHA.108.179564
  2. ↑ Mak YT, Pang CP, Tomlinson B, Zhang J, Chan YS, Mak TW, Masarei JR. Mutations in the low-density lipoprotein receptor gene in Chinese familial hypercholesterolemia patients. Arterioscler Thromb Vasc Biol. 1998 Oct;18(10):1600-5. PMID:9763532

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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