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1j3x
From Proteopedia
(Difference between revisions)
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<StructureSection load='1j3x' size='340' side='right'caption='[[1j3x]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | <StructureSection load='1j3x' size='340' side='right'caption='[[1j3x]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1j3x]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1j3x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J3X FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3x OCA], [https://pdbe.org/1j3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j3x RCSB], [https://www.ebi.ac.uk/pdbsum/1j3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3x ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/HMGB2_PIG HMGB2_PIG]] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Revision as of 07:16, 14 April 2021
Solution structure of the N-terminal domain of the HMGB2
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