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1jgk

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<StructureSection load='1jgk' size='340' side='right'caption='[[1jgk]], [[NMR_Ensembles_of_Models | 19 NMR models]]' scene=''>
<StructureSection load='1jgk' size='340' side='right'caption='[[1jgk]], [[NMR_Ensembles_of_Models | 19 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1jgk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bunca Bunca]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1jgk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bunca Bunca]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JGK FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgk OCA], [http://pdbe.org/1jgk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jgk RCSB], [http://www.ebi.ac.uk/pdbsum/1jgk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgk ProSAT]</span></td></tr>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jgk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgk OCA], [https://pdbe.org/1jgk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jgk RCSB], [https://www.ebi.ac.uk/pdbsum/1jgk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CADO_BUNCA CADO_BUNCA]] Binds and inhibits nicotinic acetylcholine receptors (nAChR). Is a reversible antagonist of muscle nAChR but a potent and poorly reversible antagonist of the neuronal alpha-7 nAChR. May exhibit differential affinities for the two binding sites on the muscle nAChR.
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[[https://www.uniprot.org/uniprot/CADO_BUNCA CADO_BUNCA]] Binds and inhibits nicotinic acetylcholine receptors (nAChR). Is a reversible antagonist of muscle nAChR but a potent and poorly reversible antagonist of the neuronal alpha-7 nAChR. May exhibit differential affinities for the two binding sites on the muscle nAChR.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 07:18, 14 April 2021

SOLUTION STRUCTURE OF CANDOXIN

PDB ID 1jgk

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