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6s8m
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state== | |
| - | + | <StructureSection load='6s8m' size='340' side='right'caption='[[6s8m]], [[Resolution|resolution]] 4.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6s8m]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6S8M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=EPB:7,11-DIHYDROXY-8,8,10,12,16-PENTAMETHYL-3-[1-METHYL-2-(2-METHYL-THIAZOL-4-YL)VINYL]-4,17-DIOXABICYCLO[14.1.0]HEPTADECANE-5,9-DIONE'>EPB</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |
| - | [[Category: | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mlv|5mlv]]</td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6s8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s8m OCA], [http://pdbe.org/6s8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6s8m RCSB], [http://www.ebi.ac.uk/pdbsum/6s8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6s8m ProSAT]</span></td></tr> |
| - | [[Category: Moores, C | + | </table> |
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/CUT7_SCHPO CUT7_SCHPO]] Could be a spindle pole body motor. On transition from G2 to M phase of the cell cycle, the spindle pole body duplicates; the daughter pole bodies seed microtubules which interdigitate to form a short spindle that elongates to span the nucleus at metaphase. Mutations at cut7 block spindle formation. [[http://www.uniprot.org/uniprot/TBA1_SCHPO TBA1_SCHPO]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [[http://www.uniprot.org/uniprot/TBB_SCHPO TBB_SCHPO]] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Loeffelholz, O von]] | ||
| + | [[Category: Moores, C A]] | ||
| + | [[Category: Cut7 motor domain]] | ||
| + | [[Category: Kinesin-5]] | ||
| + | [[Category: Microtubule]] | ||
| + | [[Category: Motor protein]] | ||
| + | [[Category: S. pombe]] | ||
Revision as of 06:14, 21 August 2019
S. pombe microtubule decorated with Cut7 motor domain in the AMPPNP state
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