6po4

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Current revision (07:32, 11 October 2023) (edit) (undo)
 
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<StructureSection load='6po4' size='340' side='right'caption='[[6po4]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6po4' size='340' side='right'caption='[[6po4]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6po4]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PO4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6po4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae_PittII Haemophilus influenzae PittII]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PO4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Adenosylhomocysteine_nucleosidase Adenosylhomocysteine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.9 3.2.2.9] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=HCS:2-AMINO-4-MERCAPTO-BUTYRIC+ACID'>HCS</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6po4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6po4 OCA], [http://pdbe.org/6po4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6po4 RCSB], [http://www.ebi.ac.uk/pdbsum/6po4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6po4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6po4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6po4 OCA], [https://pdbe.org/6po4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6po4 RCSB], [https://www.ebi.ac.uk/pdbsum/6po4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6po4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A0E1SMD9_HAEIF A0A0E1SMD9_HAEIF]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[HAMAP-Rule:MF_01684][SAAS:SAAS00064815]
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[https://www.uniprot.org/uniprot/A0A0E1SMD9_HAEIF A0A0E1SMD9_HAEIF] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[HAMAP-Rule:MF_01684][SAAS:SAAS00064815]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Adenosylhomocysteine nucleosidase]]
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[[Category: Haemophilus influenzae PittII]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Cardona-Correa A]]
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[[Category: Cardona-Correa, A]]
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[[Category: Dubrovska I]]
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[[Category: Dubrovska, I]]
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[[Category: Grimshaw S]]
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[[Category: Grimshaw, S]]
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[[Category: Kwon K]]
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[[Category: Kwon, K]]
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[[Category: Minasov G]]
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[[Category: Minasov, G]]
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[[Category: Satchell KJF]]
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[[Category: Satchell, K J.F]]
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[[Category: Shuvalova L]]
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[[Category: Shuvalova, L]]
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[[Category: 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase]]
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[[Category: Csgid]]
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[[Category: Hydrolase]]
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Current revision

2.1 Angstrom Resolution Crystal Structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (mtnN) from Haemophilus influenzae PittII.

PDB ID 6po4

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