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1onj

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<StructureSection load='1onj' size='340' side='right'caption='[[1onj]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
<StructureSection load='1onj' size='340' side='right'caption='[[1onj]], [[Resolution|resolution]] 1.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1onj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chinese_cobra Chinese cobra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ONJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1onj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chinese_cobra Chinese cobra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ONJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ONJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1onj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1onj OCA], [http://pdbe.org/1onj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1onj RCSB], [http://www.ebi.ac.uk/pdbsum/1onj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1onj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1onj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1onj OCA], [https://pdbe.org/1onj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1onj RCSB], [https://www.ebi.ac.uk/pdbsum/1onj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1onj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/3S1CC_NAJAT 3S1CC_NAJAT]] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission. Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Has a lower toxicity than cobrotoxin.<ref>PMID:9498573</ref>
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[[https://www.uniprot.org/uniprot/3S1CC_NAJAT 3S1CC_NAJAT]] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission. Produces peripheral paralysis by blocking neuromuscular transmission at the postsynaptic site. Has a lower toxicity than cobrotoxin.<ref>PMID:9498573</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 08:58, 21 April 2021

Crystal structure of Atratoxin-b from Chinese cobra venom of Naja atra

PDB ID 1onj

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