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1kna

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<StructureSection load='1kna' size='340' side='right'caption='[[1kna]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='1kna' size='340' side='right'caption='[[1kna]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1kna]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KNA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1kna]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KNA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KNA FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kna OCA], [http://pdbe.org/1kna PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kna RCSB], [http://www.ebi.ac.uk/pdbsum/1kna PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kna ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kna OCA], [https://pdbe.org/1kna PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kna RCSB], [https://www.ebi.ac.uk/pdbsum/1kna PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kna ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/HP1_DROME HP1_DROME]] Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.
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[[https://www.uniprot.org/uniprot/HP1_DROME HP1_DROME]] Structural component of heterochromatin, involved in gene repression and the modification of position-effect-variegation. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 08:49, 21 April 2021

Chromo domain of HP1 complexed with histone H3 tail containing dimethyllysine 9.

PDB ID 1kna

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