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GTP-binding protein 3D structures

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Line 32: Line 32:
**[[2b92]] - hGBP N terminal + GDP<br />
**[[2b92]] - hGBP N terminal + GDP<br />
**[[2bc9]] - hGBP N terminal + GPPNHP<br />
**[[2bc9]] - hGBP N terminal + GPPNHP<br />
-
**[[1yr7]], [[1yr8]] – PaGBP + GTP<br />
+
**[[2gao]] - hSar1A + GDP<br />
-
**[[1yr9]], [[1yra]], [[1yrb]], [[2oxr]] – PaGBP + GDP<br />
+
**[[2fa9]] – ChSar1B (mutant) + GDP – Chinese hamster<br />
-
**[[3kxi]], [[2qth]] – SsHflx + GDP<br />
+
**[[2fmx]] - ChSar1B + GDP<br />
**[[1yzn]] – yPt1 + GPPNHP<br />
**[[1yzn]] – yPt1 + GPPNHP<br />
**[[1ky2]] – yPt7 + GPPNHP<br />
**[[1ky2]] – yPt7 + GPPNHP<br />
Line 52: Line 52:
**[[2dby]] – TtYchF + GDP<br />
**[[2dby]] – TtYchF + GDP<br />
**[[1wf3]] – Tt1341 + GNP<br />
**[[1wf3]] – Tt1341 + GNP<br />
-
**[[2gao]] - hSar1A + GDP<br />
 
-
**[[2fa9]] – ChSar1B (mutant) + GDP – Chinese hamster<br />
 
-
**[[2fmx]] - ChSar1B + GDP<br />
 
**[[5a9y]], [[4zcm]] – EcBipA + G-4-phosphate <br />
**[[5a9y]], [[4zcm]] – EcBipA + G-4-phosphate <br />
**[[5a9x]], [[5a9w]], [[4zcl]] – EcBipA + GDP <br />
**[[5a9x]], [[5a9w]], [[4zcl]] – EcBipA + GDP <br />
**[[5dn8]] – EngA + GDP – ''Coxiella burnetti''<br />
**[[5dn8]] – EngA + GDP – ''Coxiella burnetti''<br />
 +
**[[1yr7]], [[1yr8]] – PaGBP + GTP<br />
 +
**[[1yr9]], [[1yra]], [[1yrb]], [[2oxr]] – PaGBP + GDP<br />
 +
**[[3kxi]], [[2qth]] – SsHflx + GDP<br />
*GTP-binding protein complex with protein
*GTP-binding protein complex with protein
Line 66: Line 66:
**[[1m2o]] – ySar1 + protein transport protein sec23<br />
**[[1m2o]] – ySar1 + protein transport protein sec23<br />
**[[6gni]] - ySar1 + protein transport protein sec23 + Sec24 + GNP<br />
**[[6gni]] - ySar1 + protein transport protein sec23 + Sec24 + GNP<br />
 +
**[[6gwp]] – yGtr1 + Gtr2 + Meh1 + Ego2 + Slm4 + GNP<br />
**[[3syn]] – BsFlhf + ATP-binding protein<br />
**[[3syn]] – BsFlhf + ATP-binding protein<br />
Line 76: Line 77:
* GTP-binding protein LepA
* GTP-binding protein LepA
-
**[[3cb4]] – EcLepA <br />
 
**[[2ywe]] – AaLepA – ''Aquifex aeolicus''<br />
**[[2ywe]] – AaLepA – ''Aquifex aeolicus''<br />
-
**[[4k8w]] – LepA – ''Streptococcus pyogenes''<br />
 
**[[2ywf]] – AaLepA + GMP-PNP<br />
**[[2ywf]] – AaLepA + GMP-PNP<br />
**[[2ywg]] - AaLepA + GTP<br />
**[[2ywg]] - AaLepA + GTP<br />
**[[2ywh]] - AaLepA + GDP<br />
**[[2ywh]] - AaLepA + GDP<br />
 +
**[[3cb4]] – EcLepA <br />
**[[3deg]] – EcLepA + A-tRNA + P-tRNA + RPS12 + RPL11 – Cryo EM<br />
**[[3deg]] – EcLepA + A-tRNA + P-tRNA + RPS12 + RPL11 – Cryo EM<br />
 +
**[[4k8w]] – LepA – ''Streptococcus pyogenes''<br />
*G protein bound to a G protein-coupled receptor
*G protein bound to a G protein-coupled receptor
Line 106: Line 107:
**[[1x3s]] – hRab-18 + GPPNHP
**[[1x3s]] – hRab-18 + GPPNHP
**[[6huf]] - hRab-27A + GNP<br />
**[[6huf]] - hRab-27A + GNP<br />
 +
**[[6s6a]], [[6s6d]] - hRagA (mutant) + RagC (mutant) + GDP + GTP<br />
**[[2atx]] – hTc10 + GPPNHP<br />
**[[2atx]] – hTc10 + GPPNHP<br />
**[[1g16]] – ySec4 + GDP<br />
**[[1g16]] – ySec4 + GDP<br />
Line 131: Line 133:
**[[6ces]] – hRag-C (mutant) + NPRL2 + NPRL3 + DEPDC5 + GNP – Cryo EM<br />
**[[6ces]] – hRag-C (mutant) + NPRL2 + NPRL3 + DEPDC5 + GNP – Cryo EM<br />
**[[6ehr]], [[5x6v]] – hRag-A + hRag-C + lamtor1 + lamtor2 + lamtor3 + lamtor4 + lamtor5<br />
**[[6ehr]], [[5x6v]] – hRag-A + hRag-C + lamtor1 + lamtor2 + lamtor3 + lamtor4 + lamtor5<br />
 +
**[[6u62]] – hRag-A + hRag-C + lamtor1 + lamtor2 + lamtor3 + lamtor4 + lamtor5 + GTP + GDP – Cryo EM<br />
 +
**[[6nzd]], [[6ulg]] – hRag-A + hRag-C + lamtor1 + lamtor2 + lamtor3 + lamtor4 + lamtor5 + folliculin + folliculin-interacting protein + GDP – Cryo EM<br />
 +
**[[6sb2]] – hRag-A + hRag-C + Mtor + Torc + Raptor + GDP + GTP – Cryo EM<br />
 +
**[[6sb0]] – hRag-A + hRag-C + Mtor + Torc + Raptor + Pro-rich Akt1 substrate + GDP + GTP – Cryo EM<br />
 +
**[[6oq3]], [[6oq4]] – hRap-1B + krev interacting trapped protein + GNP<br />
*'''Interferon-induced GTP-binding protein'''
*'''Interferon-induced GTP-binding protein'''
Line 152: Line 159:
**[[2cls]] – hRho6 + GTP<br />
**[[2cls]] – hRho6 + GTP<br />
**[[2fv8]] - hRhoB + GDP<br />
**[[2fv8]] - hRhoB + GDP<br />
 +
**[[6hxu]] - hRhoB (mutant) + GTP<br />
**[[2gcn]] – hRhoC + GDP<br />
**[[2gcn]] – hRhoC + GDP<br />
**[[2gco]] – hRhoC + GPPNHP<br />
**[[2gco]] – hRhoC + GPPNHP<br />
Line 166: Line 174:
**[[1cc0]] – hRhoA + GDP-dissociation inhibitor + GDP<br />
**[[1cc0]] – hRhoA + GDP-dissociation inhibitor + GDP<br />
**[[6bca]] - hRhoA + kinase anchor protein + GTP<br />
**[[6bca]] - hRhoA + kinase anchor protein + GTP<br />
 +
**[[6sge]] - hRhoB + nanobody + GTP<br />
**[[3a58]] – yRho1 (mutant) + exocyst complex component Sec3 + cancidas<br />
**[[3a58]] – yRho1 (mutant) + exocyst complex component Sec3 + cancidas<br />
Line 186: Line 195:
**[[1ees]] – hCdc42 + MapK3 peptide - NMR<br />
**[[1ees]] – hCdc42 + MapK3 peptide - NMR<br />
**[[1doa]] - hCdc42 + GDP-dissociation inhibitor<br />
**[[1doa]] - hCdc42 + GDP-dissociation inhibitor<br />
 +
**[[6tky]], [[6tkz]] - hCdc42 + dedicator of cytokinesis protein<br />
**[[2ngr]] – hCdc42 + GTPase-activating protein C terminal + GDP<br />
**[[2ngr]] – hCdc42 + GTPase-activating protein C terminal + GDP<br />
**[[1am4]] – hCdc42 + GTPase-activating protein rhoGAP + GNP<br />
**[[1am4]] – hCdc42 + GTPase-activating protein rhoGAP + GNP<br />
Line 199: Line 209:
**[[5upl]], [[5upk]] - hCdc42 + PAK 4<br />
**[[5upl]], [[5upk]] - hCdc42 + PAK 4<br />
**[[5fi1]] - hCdc42 + PTDINS dependent RAC exchanger<br />
**[[5fi1]] - hCdc42 + PTDINS dependent RAC exchanger<br />
 +
**[[6siu]] - hCdc42 + IBPA + GDP<br />
*'''Rac-like GTP-binding protein'''
*'''Rac-like GTP-binding protein'''
Line 280: Line 291:
**[[3gjx]] – hRan + snurportin 1 + exportin 1 + GTP <br />
**[[3gjx]] – hRan + snurportin 1 + exportin 1 + GTP <br />
**[[3nby]], [[3nbz]], [[3nc0]] – hRan (mutant) + snurportin 1 + exportin 1 + GTP <br />
**[[3nby]], [[3nbz]], [[3nc0]] – hRan (mutant) + snurportin 1 + exportin 1 + GTP <br />
 +
**[[6tvo]] – hRan (mutant) + exportin 1 + leptomycin + GTP <br />
 +
**[[6x2p]], [[6x2s]] – hRan (mutant) + exportin 1 + Mkk1 + GNP <br />
**[[1k5d]], [[5zpu]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GTP analog<br />
**[[1k5d]], [[5zpu]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GTP analog<br />
**[[1k5g]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GDP <br />
**[[1k5g]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GDP <br />
Line 286: Line 299:
**[[5jlj]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP + inhibitor<br />
**[[5jlj]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP + inhibitor<br />
**[[4wvf]] – hRan + Ran-specific GTPase-activating protein + CRM1P + GNP + inhibitor<br />
**[[4wvf]] – hRan + Ran-specific GTPase-activating protein + CRM1P + GNP + inhibitor<br />
-
**[[6cit]] – hRan + Ran-specific GTPase-activating protein + exportin + NS2<br />
+
**[[6cit]], [[6kft]] – hRan + Ran-specific GTPase-activating protein + exportin + NS2 + GNP<br />
 +
**[[6x2r]] – hRan + Ran-specific GTPase-activating protein + exportin + Eif4E + GNP<br />
 +
**[[6x2u]], [[6x2v]], [[6x2w]] – hRan + Ran-specific GTPase-activating protein + exportin + Pki-alpha peptide + GNP<br />
 +
**[[6x2x]] – hRan + Ran-specific GTPase-activating protein + exportin + Mkk1 peptide + GNP<br />
 +
**[[6x2y]] – hRan + Ran-specific GTPase-activating protein + exportin + diaphanous homolog peptide + GNP<br />
**[[6a3e]], [[6a3c]], [[6a3b]], [[6a3a]], [[6a38]] – hRan + Ran-specific GTPase-activating protein + exportin + NES + GTP<br />
**[[6a3e]], [[6a3c]], [[6a3b]], [[6a3a]], [[6a38]] – hRan + Ran-specific GTPase-activating protein + exportin + NES + GTP<br />
**[[5ytb]], [[5yst]], [[5yro]] – hRan (mutant) + Ran-specific GTPase-activating protein + exportin + GTP<br />
**[[5ytb]], [[5yst]], [[5yro]] – hRan (mutant) + Ran-specific GTPase-activating protein + exportin + GTP<br />
Line 296: Line 313:
**[[5dis]] – hRan (mutant) + exportin 1 + RNA U transporter + Nup214 + GTP <br />
**[[5dis]] – hRan (mutant) + exportin 1 + RNA U transporter + Nup214 + GTP <br />
**[[3a6p]] – dRan + pre-microRNA + exportin 5 + peptide <br />
**[[3a6p]] – dRan + pre-microRNA + exportin 5 + peptide <br />
 +
**[[5yu6]] – dRan + exportin 5 + peptide + GTP<br />
**[[3icq]] – yRan + RNA + exportin T <br />
**[[3icq]] – yRan + RNA + exportin T <br />
**[[3m1i]] – yRan + Ran-specific GTPase-activating protein + exportin 1 + GTP <br />
**[[3m1i]] – yRan + Ran-specific GTPase-activating protein + exportin 1 + GTP <br />
 +
 +
*Small GTP-binding protein
 +
 +
**[[5kh0]] - GBP – ''Thermosipho melanesiensis''<br />
 +
 +
*Small GTP-binding protein ERA
 +
 +
**[[1ega]] – EcERA <br />
 +
**[[3ieu]] – EcERA + GDP <br />
 +
**[[3iev]] – AaERA + RNA + Mg-GNP <br />
 +
**[[1x1l]] – TtERA + RNA – Cryo EM<br />
 +
**[[1x18]] – TtERA + RNA + RPS2 + RPS7 + RPS11 + RPS18 – Cryo EM<br />
 +
 +
*Small GTP-binding protein Gem
 +
 +
**[[2cjw]], [[2ht6]], [[2g3y]] – hGem G domain + GDP<br />
 +
 +
*Small GTP-binding protein Rheb
 +
 +
**[[1xtq]], [[5yxh]] – hRheb + GDP<br />
 +
**[[7bta]], [[7btc]] - hRheb (mutant) + GDP <br />
 +
**[[1xts]] - hRheb + GTP<br />
 +
**[[1xtr]] - hRheb + GPPNHP<br />
 +
**[[7btd]] - hRheb (mutant) + GPPNHP <br />
 +
**[[3sea]] - hRheb + GDP + GNP<br />
 +
**[[6bt0]], [[6bsx]] - hRheb + GDP + inhibitor<br />
 +
**[[3t5g]] – hRheb + GMP-PDE delta<br />
 +
**[[4o25]] – mRheb + GTP - mouse<br />
 +
**[[4o2l]] - mRheb (mutant) + GTP <br />
 +
**[[4o2r]] - mRheb (mutant) + GDP <br />
 +
**[[2l0x]] – rRheb + GDP<br />
 +
*'''Small GTPase h-Ras''' see [[GTPase HRas]]
*'''Small GTPase h-Ras''' see [[GTPase HRas]]

Revision as of 10:28, 10 August 2020

3D Structures of GTP-binding protein

Updated on 10-August-2020


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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