Histidine triad nucleotide-binding protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 18: Line 18:
</StructureSection>
</StructureSection>
- 
-
==3D structures of histidine triad nucleotide-binding protein==
 
- 
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 
-
{{#tree:id=OrganizedByTopic|openlevels=0|
 
- 
-
*HINT1 or adenosine 5’-monophosphoramidase
 
- 
-
**[[1kpa]], [[1kpb]], [[1kpc]], [[6g9z]], [[5o8i]], [[4zkv]] – hHINT – human<br />
 
-
**[[5waa]], [[5ipb]] – hHINT (mutant) <br />
 
-
**[[6rhn]] – rHINT - rabbit<br />
 
-
**[[3o1z]] – rHINT (mutant) <br />
 
- 
-
*HINT1 complexes
 
- 
-
**[[1av5]], [[1kpe]] – hHINT + adenosine derivative<br />
 
-
**[[1kpf]], [[3tw2]], [[6b42]], [[5klz]], [[5km0]], [[5km1]], [[5km2]], [[5km3]], [[5ed3]] – hHINT + nucleotide <br />
 
-
**[[5ed6]] – hHINT (mutant) + nucleotide <br />
 
-
**[[5km4]], [[4zkl]] – hHINT + nucleotide derivative<br />
 
-
**[[5ipd]], [[5ipe]] – hHINT + phosphoramidate derivative<br />
 
-
**[[5kly]], [[5km6]], [[5kma]], [[5ipc]] – hHINT (mutant) + phosphoramidate derivative<br />
 
-
**[[4eqe]] – hHINT + Lys-AMS <br />
 
-
**[[4eqg]] – hHINT + Ala-AMS <br />
 
-
**[[5kmc]] – hHINT + adenosine-phosphoramidate <br />
 
-
**[[5wa8]], [[5wa9]] – hHINT (mutant) + Ala-phosphoramidate <br />
 
-
**[[5kmb]] – hHINT (mutant) + Trp-phosphoramidate <br />
 
-
**[[4eqh]] – hHINT + Trp-AMS <br />
 
-
**[[5i2e]], [[5i2f]] – hHINT + sulfamate inhibitor<br />
 
-
**[[5emt]] – hHINT + Cu inhibitor <br />
 
-
**[[3rhn]] – rHINT + GMP <br />
 
-
**[[4rhn]], [[3qgz]] – rHINT + adenosine<br />
 
-
**[[1rzy]], [[5rhn]] – rHINT + adenosine derivative<br />
 
-
**[[3o1c]], [[3o1x]] – rHINT (mutant) + adenosine <br />
 
- 
-
*HINT2
 
- 
-
**[[4inc]], [[4njx]], [[4njy]], [[4njz]], [[4nk0]] – hHINT <br />
 
-
**[[5km9]] – hHINT + adenosine<br />
 
-
**[[6km8]] – hHINT + cidofovir<br />
 
-
**[[6km5]] – hHINT + triciribine derivative<br />
 
-
**[[4ini]] – hHINT + AMP <br />
 
- 
-
*FHIT
 
- 
-
**[[1fit]], [[2fit]], [[4fit]] – hFHIT <br />
 
-
**[[3fit]] – hFHIT + AMP <br />
 
-
**[[5fit]], [[6fit]] – hFHIT + adenosine derivative<br />
 
-
**[[1fhi]] – hFHIT + ApppA derivative<br />
 
-
**[[2fhi]] – hFHIT (mutant) + ApppA derivative<br />
 
-
}}
 
== References ==
== References ==

Revision as of 10:00, 25 July 2019

Structure of rabbit HINT1 complex with GMP (PDB code 3rhn).

Drag the structure with the mouse to rotate

References

  1. ↑ Linde CI, Feng B, Wang JB, Golovina VA. Histidine triad nucleotide-binding protein 1 (HINT1) regulates Ca(2+) signaling in mouse fibroblasts and neuronal cells via store-operated Ca(2+) entry pathway. Am J Physiol Cell Physiol. 2013 Jun 1;304(11):C1098-104. doi:, 10.1152/ajpcell.00073.2013. Epub 2013 Apr 10. PMID:23576580 doi:http://dx.doi.org/10.1152/ajpcell.00073.2013
  2. ↑ Wistuba II, Ashfaq R, Maitra A, Alvarez H, Riquelme E, Gazdar AF. Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma. Am J Pathol. 2002 Jun;160(6):2073-9. PMID:12057912 doi:http://dx.doi.org/10.1016/S0002-9440(10)61157-1
  3. ↑ Zochbauer-Muller S, Wistuba II, Minna JD, Gazdar AF. Fragile histidine triad (FHIT) gene abnormalities in lung cancer. Clin Lung Cancer. 2000 Nov;2(2):141-5. PMID:14731325
  4. ↑ Wierzbicki PM, Adrych K, Kartanowicz D, Wypych J, Stanislawowski M, Zwolinska-Wcislo M, Celinski K, Skrodzka D, Godlewski J, Korybalski B, Smoczynski M, Kmiec Z. Overexpression of the fragile histidine triad (FHIT) gene in inflammatory bowel disease. J Physiol Pharmacol. 2009 Oct;60 Suppl 4:57-62. PMID:20083852
  5. ↑ Wierzbicki PM, Adrych K, Kartanowicz D, Dobrowolski S, Stanislawowski M, Chybicki J, Godlewski J, Korybalski B, Smoczynski M, Kmiec Z. Fragile histidine triad (FHIT) gene is overexpressed in colorectal cancer. J Physiol Pharmacol. 2009 Oct;60 Suppl 4:63-70. PMID:20083853
  6. ↑ Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM. Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nat Struct Biol. 1997 Mar;4(3):231-8. PMID:9164465

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Histidine_triad_nucleotide-binding_protein"
Personal tools