6mh5

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'''Unreleased structure'''
 
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The entry 6mh5 is ON HOLD until Paper Publication
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==Crystal Structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Staphylococcus schleiferi in complex with Fosmidomycin (FOM)==
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<StructureSection load='6mh5' size='340' side='right'caption='[[6mh5]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
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Authors: Lee, S.G., Jez, J.M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6mh5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MH5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MH5 FirstGlance]. <br>
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Description: Crystal Structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Staphylococcus schleiferi in complex with Fosmidomycin (FOM)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FOM:3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC+ACID'>FOM</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-deoxy-D-xylulose-5-phosphate_reductoisomerase 1-deoxy-D-xylulose-5-phosphate reductoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.267 1.1.1.267] </span></td></tr>
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[[Category: Lee, S.G]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mh5 OCA], [http://pdbe.org/6mh5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mh5 RCSB], [http://www.ebi.ac.uk/pdbsum/6mh5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mh5 ProSAT]</span></td></tr>
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[[Category: Jez, J.M]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/A0A0K1A7V6_9STAP A0A0K1A7V6_9STAP]] Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).[HAMAP-Rule:MF_00183][SAAS:SAAS00327577]
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__TOC__
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</StructureSection>
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[[Category: 1-deoxy-D-xylulose-5-phosphate reductoisomerase]]
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[[Category: Large Structures]]
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[[Category: Jez, J M]]
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[[Category: Lee, S G]]
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[[Category: Fosmidomycin]]
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[[Category: Glpt]]
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[[Category: Mep pathway]]
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[[Category: Oxidoreductase]]
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[[Category: Reductoisomerase]]
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[[Category: Staphylococci]]

Revision as of 09:42, 18 March 2020

Crystal Structure of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Staphylococcus schleiferi in complex with Fosmidomycin (FOM)

PDB ID 6mh5

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