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Histone deacetylase 3D structures
From Proteopedia
(Difference between revisions)
(New page: == 3D Structures of histone deacetylase == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''HDAC class I''' *HD...) |
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**[[3hgq]], [[3hgt]] – hHDAC1 subunit 3<br /> | **[[3hgq]], [[3hgt]] – hHDAC1 subunit 3<br /> | ||
**[[5icn]] – hHDAC1 + MTA1 + peptide<br /> | **[[5icn]] – hHDAC1 + MTA1 + peptide<br /> | ||
| + | **[[6z2j]], [[6z2k]] – hHDAC1 + DNTTIP1 + Midac deacetylase – Cryo EM<br /> | ||
**[[5j8j]] – yHDAC1 residues 457-698 – yeast<br /> | **[[5j8j]] – yHDAC1 residues 457-698 – yeast<br /> | ||
| Line 16: | Line 17: | ||
**[[3max]] – hHDAC2 + amide derivative <br /> | **[[3max]] – hHDAC2 + amide derivative <br /> | ||
| - | **[[4lxz]] – hHDAC2 core domain + SAHA<br /> | + | **[[4lxz]], [[6g3o]] – hHDAC2 core domain + SAHA<br /> |
| - | **[[4ly1]], [[5iwg]], [[5ix0]] – hHDAC2 core domain + inhibitor<br /> | + | **[[4ly1]], [[5iwg]], [[5ix0]], [[6wbz]], [[6wbw]], [[6xdm]], [[6xeb]], [[6xec]] – hHDAC2 core domain + inhibitor<br /> |
*HDAC3 | *HDAC3 | ||
| Line 27: | Line 28: | ||
**[[3ew8]], [[3ezp]], [[3ezt]], [[3f06]] – hHDAC8 (mutant)<br /> | **[[3ew8]], [[3ezp]], [[3ezt]], [[3f06]] – hHDAC8 (mutant)<br /> | ||
**[[3sff]], [[3sfh]] – hHDAC8 + inhibitor<br /> | **[[3sff]], [[3sfh]] – hHDAC8 + inhibitor<br /> | ||
| + | **[[4qa1]], [[4qa2]], [[4qa3]], [[4qa4]] - hHDAC8 (mutant) + inhibitor<br /> | ||
**[[1t64]], [[3f0r]], [[5ths]] – hHDAC8 + trichostatin A <br /> | **[[1t64]], [[3f0r]], [[5ths]] – hHDAC8 + trichostatin A <br /> | ||
**[[5tht]], [[5thu]], [[5thv]], [[5dc5]], [[5d1b]] - hHDAC8 (mutant) + amide derivative<br /> | **[[5tht]], [[5thu]], [[5thv]], [[5dc5]], [[5d1b]] - hHDAC8 (mutant) + amide derivative<br /> | ||
| - | **[[1t67]], [[1w22]], [[1vkg]], [[3f07]] - hHDAC8 + amide derivative<br /> | + | **[[1t67]], [[1w22]], [[1vkg]], [[3f07]], [[6oda]], [[6odb]], [[6odc]] - hHDAC8 + amide derivative<br /> |
**[[1t69]] - hHDAC8 + SAHA<br /> | **[[1t69]] - hHDAC8 + SAHA<br /> | ||
**[[4qa0]] - hHDAC8 (mutant) + SAHA<br /> | **[[4qa0]] - hHDAC8 (mutant) + SAHA<br /> | ||
**[[5fcw]], [[5fue]] - hHDAC8 + hydroxamate<br /> | **[[5fcw]], [[5fue]] - hHDAC8 + hydroxamate<br /> | ||
**[[5vi6]] - hHDAC8 + trapoxin A<br /> | **[[5vi6]] - hHDAC8 + trapoxin A<br /> | ||
| - | **[[4qa1]], [[4qa2]], [[4qa3]], [[4qa4]] - hHDAC8 (mutant) + inhibitor<br /> | ||
**[[2v5w]] – hHDAC8 + tripeptide substrate<br /> | **[[2v5w]] – hHDAC8 + tripeptide substrate<br /> | ||
**[[4qa5]], [[4qa6]], [[4qa7]], [[3ewf]], [[5dc8]], [[5dc7]], [[5dc6]], [[5d1d]], [[5d1c]] - hHDAC8 (mutant) + tetrapeptide substrate<br /> | **[[4qa5]], [[4qa6]], [[4qa7]], [[3ewf]], [[5dc8]], [[5dc7]], [[5dc6]], [[5d1d]], [[5d1c]] - hHDAC8 (mutant) + tetrapeptide substrate<br /> | ||
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**[[2v5x]] - hHDAC8 (mutant) + octanediamide derivative<br /> | **[[2v5x]] - hHDAC8 (mutant) + octanediamide derivative<br /> | ||
**[[4bz5]] – SmHDAC8 – ''Schistosoma mansoni''<br /> | **[[4bz5]] – SmHDAC8 – ''Schistosoma mansoni''<br /> | ||
| - | **[[4bz7]], [[4bz8]], [[4bz9]], [[4cqf]], [[6hsz]], [[6ht8]], [[6htg]], [[6hth]], [[6hti]], [[6htt]], [[6htz]], [[6hu0]], [[6hu1]], [[6hu2]], [[6hu3]], [[6hsh]], [[6hrq]], [[6hqy]] – SmHDAC8 + inhibitor<br /> | + | **[[4bz7]], [[4bz8]], [[4bz9]], [[4cqf]], [[6hsz]], [[6ht8]], [[6htg]], [[6hth]], [[6hti]], [[6htt]], [[6htz]], [[6hu0]], [[6hu1]], [[6hu2]], [[6hu3]], [[6hsh]], [[6hrq]], [[6hqy]], [[6tld]] – SmHDAC8 + inhibitor<br /> |
**[[6hsk]], [[6hsf]], [[6hsg]] – SmHDAC8 (mutant) + inhibitor<br /> | **[[6hsk]], [[6hsf]], [[6hsg]] – SmHDAC8 (mutant) + inhibitor<br /> | ||
**[[4bz6]], [[6gxw]], [[6gxu]], [[6gxa]], [[6gx3]], [[6fu1]] – SmHDAC8 + SAHA derivative<br /> | **[[4bz6]], [[6gxw]], [[6gxu]], [[6gxa]], [[6gx3]], [[6fu1]] – SmHDAC8 + SAHA derivative<br /> | ||
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**[[1tqe]] – mHDAC9 + myocyte-specific enhancer factor + DNA – mouse | **[[1tqe]] – mHDAC9 + myocyte-specific enhancer factor + DNA – mouse | ||
| + | |||
| + | *HDAC10 or polyamine deacetylase 10 | ||
| + | |||
| + | **[[6ufn]], [[6ufo]], [[6uhu]], [[6uhv]], [[6uii]], [[6uij]], [[6uil]], [[6uim]], [[6wbq]], [[6wdv]], [[6wdw]], [[6wdx]], [[6wdy]] – zHDAC10 + inhibitor - zebrafish<br /> | ||
| + | **[[6vnq]] – zHDAC10 (mutant) + inhibitor <br /> | ||
*HDAC | *HDAC | ||
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**[[3phd]] - hHDAC6 + polyubiquitin<br /> | **[[3phd]] - hHDAC6 + polyubiquitin<br /> | ||
**[[5kh3]], [[5kh7]], [[5kh9]], [[5b8d]], [[6ce6]], [[6ce8]], [[6cea]], [[6cec]], [[6ced]], [[6cee]], [[6cef]], [[5wpb]], [[5wbn]] – hHDAC6 zinc finger + inhibitor<br /> | **[[5kh3]], [[5kh7]], [[5kh9]], [[5b8d]], [[6ce6]], [[6ce8]], [[6cea]], [[6cec]], [[6ced]], [[6cee]], [[6cef]], [[5wpb]], [[5wbn]] – hHDAC6 zinc finger + inhibitor<br /> | ||
| - | **[[5eem]] – zHDAC6 catalytic domain | + | **[[5eem]] – zHDAC6 catalytic domain<br /> |
| - | **[[6cgp]], [[5wgm]], [[5wgl]], [[5wgi]], [[5wgk]], [[5g0j]], [[5g0i]], [[5g0h]], [[5g0g]], [[5g0f]], [[5efh]], [[5efg]], [[5efb]], [[5ef7]], [[5ef8]], [[5een]], [[5eek]], [[5eef]], [[6mr5]], [[6dvo]], [[6dvn]], [[6dvm]], [[6dvl]], [[6cw8]] – zHDAC6 catalytic domain + inhibitor <br /> | + | **[[6cgp]], [[5wgm]], [[5wgl]], [[5wgi]], [[5wgk]], [[5g0j]], [[5g0i]], [[5g0h]], [[5g0g]], [[5g0f]], [[5efh]], [[5efg]], [[5efb]], [[5ef7]], [[5ef8]], [[5een]], [[5eek]], [[5eef]], [[6mr5]], [[6dvo]], [[6dvn]], [[6dvm]], [[6dvl]], [[6cw8]], [[6pye]], [[6pzo]], [[6pzr]], [[6pzs]], [[6pzu]], [[6q0z]], [[6r0k]], [[6thv]], [[6uo2]], [[6uo3]], [[6uo5]], [[6vnr]] – zHDAC6 catalytic domain + inhibitor <br /> |
| + | **[[6uo4]], [[6uo7]], [[6uob]], [[6uoc]] – zHDAC6 catalytic domain (mutant) + inhibitor <br /> | ||
**[[5eei]], [[6css]], [[6csr]], [[6csq]], [[6csp]], [[5w5k]] – zHDAC6 catalytic domain + SAHA derivative<br /> | **[[5eei]], [[6css]], [[6csr]], [[6csq]], [[6csp]], [[5w5k]] – zHDAC6 catalytic domain + SAHA derivative<br /> | ||
**[[5efn]], [[5efk]], [[53fj]] – zHDAC6 catalytic domain (mutant) + peptide <br /> | **[[5efn]], [[5efk]], [[53fj]] – zHDAC6 catalytic domain (mutant) + peptide <br /> | ||
| + | *HDAC15 | ||
| + | |||
| + | **[[6j6t]] – HDAC15 HD domain – ''Arabidopsis thaliana''<br /> | ||
*'''HDAC class III''' | *'''HDAC class III''' | ||
Revision as of 08:08, 19 August 2020
3D Structures of histone deacetylase
Updated on 19-August-2020
