Phosphoserine phosphatase

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*Phosphoserine phosphatase binary complex
*Phosphoserine phosphatase binary complex
 +
**[[1l8l]] – hPSP (mutant) + phosphono-propionic acid – human<br />
 +
**[[1nnl]], [[6hyj]] – hPSP + Ca<br />
**[[3p96]], [[5is2]] – MaPSP + Mg – ''Mycobacterium avium''<br />
**[[3p96]], [[5is2]] – MaPSP + Mg – ''Mycobacterium avium''<br />
**[[5it0]], [[5it4]], [[5jjb]], [[5t41]] – MaPSP (mutant) + Mg<br />
**[[5it0]], [[5it4]], [[5jjb]], [[5t41]] – MaPSP (mutant) + Mg<br />
**[[3m1y]] – PSP + Mg – ''Helicobacter pylori''<br />
**[[3m1y]] – PSP + Mg – ''Helicobacter pylori''<br />
**[[1l7o]] – MjPSP (mutant) + Zn – ''Methanocaldococcus jannaschi''i<br />
**[[1l7o]] – MjPSP (mutant) + Zn – ''Methanocaldococcus jannaschi''i<br />
-
**[[1l8l]] – hPSP (mutant) + phosphono-propionic acid – human<br />
 
-
**[[1nnl]] – hPSP + Ca<br />
 
**[[3w40]], [[3w41]] – BsPSP + Mg<br />
**[[3w40]], [[3w41]] – BsPSP + Mg<br />
**[[3w42]], [[3w43]], [[3w44]] – BsPSP + Mn<br />
**[[3w42]], [[3w43]], [[3w44]] – BsPSP + Mn<br />
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*Phosphoserine phosphatase ternary complex
*Phosphoserine phosphatase ternary complex
 +
**[[6q6j]] – hPSP + Ca + substrate analog<br />
 +
**[[6hyy]] – hPSP + PO4 + serine + <br />
**[[1l8o]] – hPSP (mutant) + serine + PO4<br />
**[[1l8o]] – hPSP (mutant) + serine + PO4<br />
**[[1f5s]], [[1j97]], [[1l7m]] – MjPSP + PO4 + Mg<br />
**[[1f5s]], [[1j97]], [[1l7m]] – MjPSP + PO4 + Mg<br />

Revision as of 09:13, 21 November 2019

Human phosphoserine phosphatase dimer complex with serine and phosphate 1l8o

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3D structures of phosphoserine phosphatase

Updated on 21-November-2019

References

  1. NEUHAUS FC, BYRNE WL. Metabolism of phosphoserine. II. Purification and properties of O-phosphoserine phosphatase. J Biol Chem. 1959 Jan;234(1):113-21. PMID:13610904
  2. Jaeken J, Detheux M, Fryns JP, Collet JF, Alliet P, Van Schaftingen E. Phosphoserine phosphatase deficiency in a patient with Williams syndrome. J Med Genet. 1997 Jul;34(7):594-6. PMID:9222972
  3. Kim HY, Heo YS, Kim JH, Park MH, Moon J, Kim E, Kwon D, Yoon J, Shin D, Jeong EJ, Park SY, Lee TG, Jeon YH, Ro S, Cho JM, Hwang KY. Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase. J Biol Chem. 2002 Nov 29;277(48):46651-8. Epub 2002 Sep 3. PMID:12213811 doi:10.1074/jbc.M204866200

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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