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6r12

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Current revision (12:12, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6r12' size='340' side='right'caption='[[6r12]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='6r12' size='340' side='right'caption='[[6r12]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6r12]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R12 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6R12 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6r12]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetospirillum_gryphiswaldense_MSR-1 Magnetospirillum gryphiswaldense MSR-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6R12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6R12 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EF2:S-THALIDOMIDE'>EF2</scene>, <scene name='pdbligand=JOT:~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-2-phenyl-ethanamide'>JOT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=UNK:UNKNOWN'>UNK</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EF2:S-THALIDOMIDE'>EF2</scene>, <scene name='pdbligand=JOT:~{N}-[(3~{S})-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-2-phenyl-ethanamide'>JOT</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6r12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r12 OCA], [http://pdbe.org/6r12 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6r12 RCSB], [http://www.ebi.ac.uk/pdbsum/6r12 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6r12 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6r12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6r12 OCA], [https://pdbe.org/6r12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6r12 RCSB], [https://www.ebi.ac.uk/pdbsum/6r12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6r12 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A4TVL0_9PROT A4TVL0_9PROT]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hartmann, M D]]
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[[Category: Magnetospirillum gryphiswaldense MSR-1]]
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[[Category: Heim, C]]
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[[Category: Hartmann MD]]
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[[Category: Hydrolysis product]]
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[[Category: Heim C]]
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[[Category: Protac]]
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[[Category: Protein degradation]]
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[[Category: Proteolysis targeting chimera]]
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[[Category: Signaling protein]]
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Current revision

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 7b

PDB ID 6r12

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