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3ngx
From Proteopedia
(Difference between revisions)
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<StructureSection load='3ngx' size='340' side='right'caption='[[3ngx]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='3ngx' size='340' side='right'caption='[[3ngx]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3ngx]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3ngx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NGX FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ngl|3ngl]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3ngl|3ngl]]</div></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ngx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ngx OCA], [https://pdbe.org/3ngx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ngx RCSB], [https://www.ebi.ac.uk/pdbsum/3ngx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ngx ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/FOLD_THEAC FOLD_THEAC]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 07:01, 12 May 2022
Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum
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Categories: Large Structures | Hwang, K W | Lee, W H | Sung, M W | 10-methenyltetrahydrofolate | 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate | 10-methylenetetrahydrofolate to 5 | Catalyzes the oxidation of 5 | Hydrolase | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase | Oxidoreductase | The hydrolysis of 5
