5qtp

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m (Protected "5qtp" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5qtp is ON HOLD
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==PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with AE-0227==
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<StructureSection load='5qtp' size='340' side='right'caption='[[5qtp]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
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Authors: Dubianok, Y., Krojer, T., Kovacs, H., Moriaud, F., Wright, N., Strain-Damerell, C., Burgess-Brown, N., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qtp]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QTP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QTP FirstGlance]. <br>
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Description: PanDDA analysis group deposition --Crystal Structure of NUDT5 in complex with AE-0227
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PWJ:8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-7-carbonitrile'>PWJ</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qtp OCA], [http://pdbe.org/5qtp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qtp RCSB], [http://www.ebi.ac.uk/pdbsum/5qtp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qtp ProSAT]</span></td></tr>
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[[Category: Moriaud, F]]
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</table>
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[[Category: Wright, N]]
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== Function ==
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[[Category: Arrowsmith, C.H]]
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[[http://www.uniprot.org/uniprot/NUDT5_HUMAN NUDT5_HUMAN]] Hydrolyzes with similar activities ADP-ribose ADP-mannose, ADP-glucose, 8-oxo-GDP and 8-oxo-dGDP. Can also hydrolyze other nucleotide sugars with low activity.<ref>PMID:17052728</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
[[Category: Burgess-Brown, N]]
[[Category: Burgess-Brown, N]]
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[[Category: Delft, F von]]
[[Category: Dubianok, Y]]
[[Category: Dubianok, Y]]
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[[Category: Edwards, A]]
[[Category: Kovacs, H]]
[[Category: Kovacs, H]]
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[[Category: Edwards, A]]
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[[Category: Krojer, T]]
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[[Category: Moriaud, F]]
[[Category: Strain-Damerell, C]]
[[Category: Strain-Damerell, C]]
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[[Category: Krojer, T]]
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[[Category: Wright, N]]
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[[Category: Von Delft, F]]
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[[Category: Hydrolase]]
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[[Category: Bountra, C]]
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[[Category: Pandda]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Xchemexplorer]]

Revision as of 09:00, 25 December 2019

PanDDA analysis group deposition -- Crystal Structure of NUDT5 in complex with AE-0227

PDB ID 5qtp

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