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3eml
From Proteopedia
(Difference between revisions)
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<StructureSection load='3eml' size='340' side='right'caption='[[3eml]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='3eml' size='340' side='right'caption='[[3eml]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3eml]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3eml]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EML OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EML FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene>, <scene name='pdbligand=ZMA:4-{2-[(7-AMINO-2-FURAN-2-YL[1,2,4]TRIAZOLO[1,5-A][1,3,5]TRIAZIN-5-YL)AMINO]ETHYL}PHENOL'>ZMA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eml FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eml OCA], [https://pdbe.org/3eml PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eml RCSB], [https://www.ebi.ac.uk/pdbsum/3eml PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eml ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/AA2AR_HUMAN AA2AR_HUMAN]] Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]] | *[[Adenosine A2A receptor 3D structures|Adenosine A2A receptor 3D structures]] | ||
| - | *[[G protein-coupled receptor|G protein-coupled receptor]] | ||
*[[Lysozyme 3D structures|Lysozyme 3D structures]] | *[[Lysozyme 3D structures|Lysozyme 3D structures]] | ||
== References == | == References == | ||
Revision as of 09:10, 23 February 2022
The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385.
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Categories: Human | Large Structures | ATCG3D, Accelerated Technologies Center for Gene to 3D Structure | Cherezov, V | Chien, E Y.T | GPCR, GPCR Network | Griffith, M T | Hanson, M A | Ijzerman, A P | Jaakola, V P | Lane, J R | Stevens, R C | Accelerated technologies center for gene to 3d structure | Adenosine | Atcg3d | Caffeine | Gpcr | Gpcr network | Lcp | Membrane protein | Mesophase | PSI, Protein structure initiative | Receptor | Structural genomic
