Rho GTPase
From Proteopedia
(Difference between revisions)
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*<scene name='75/752220/Cv/7'>GDP binding site</scene> | *<scene name='75/752220/Cv/7'>GDP binding site</scene> | ||
*<scene name='75/752220/Cv/8'>AlF4 and Mg+2 ion binding site</scene>. | *<scene name='75/752220/Cv/8'>AlF4 and Mg+2 ion binding site</scene>. | ||
| + | ==3D structures of Rho GTPase== | ||
| + | [[Rho GTPase 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
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**[[1m7b]] – hRhoE + GTP <br /> | **[[1m7b]] – hRhoE + GTP <br /> | ||
| - | **[[1gwn]] – mRhoE core domain + GTP <br /> | ||
**[[2v55]] – hRhoE + ROCKI + GTP + ANP<br /> | **[[2v55]] – hRhoE + ROCKI + GTP + ANP<br /> | ||
| + | **[[1gwn]] – mRhoE core domain + GTP <br /> | ||
| - | *Miro1 | + | *Miro1 or mitochondrial Rho GTPase 1 |
| + | **[[6d71]] – hMiro1 N-terminal + GTP <br /> | ||
**[[5kso]], [[5ksp]], [[5ksy]] – hMiro1 C-terminal + GDP <br /> | **[[5kso]], [[5ksp]], [[5ksy]] – hMiro1 C-terminal + GDP <br /> | ||
| - | **[[5ksz]] – hMiro1 EF hand and kinase domain | + | **[[5ksz]] – hMiro1 EF hand and kinase domain residues 177-592 - GMPPCP <br /> |
**[[5kty]], [[5ku1]] – hMiro1 EF hand and kinase domain + GDP <br /> | **[[5kty]], [[5ku1]] – hMiro1 EF hand and kinase domain + GDP <br /> | ||
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**[[4c0l]] – DmMiro + GDP <br /> | **[[4c0l]] – DmMiro + GDP <br /> | ||
| + | *Rho1 | ||
| + | |||
| + | **[[5zvp]] – Rho1 + GDP – ''Aspergillus fumigatus''<br /> | ||
}} | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:56, 15 December 2019
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3D structures of Rho GTPase
Updated on 15-December-2019
References
- ↑ Sepp KJ, Auld VJ. RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia. Development. 2003 May;130(9):1825-35. PMID:12642488
- ↑ Fransson A, Ruusala A, Aspenstrom P. Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis. J Biol Chem. 2003 Feb 21;278(8):6495-502. Epub 2002 Dec 12. PMID:12482879 doi:http://dx.doi.org/10.1074/jbc.M208609200
- ↑ Zhou J, Hayakawa Y, Wang TC, Bass AJ. RhoA mutations identified in diffuse gastric cancer. Cancer Cell. 2014 Jul 14;26(1):9-11. doi: 10.1016/j.ccr.2014.06.022. PMID:25026207 doi:http://dx.doi.org/10.1016/j.ccr.2014.06.022
- ↑ Jin L, Burnett AL. RhoA/Rho-kinase in erectile tissue: mechanisms of disease and therapeutic insights. Clin Sci (Lond). 2006 Feb;110(2):153-65. PMID:16411892 doi:http://dx.doi.org/10.1042/CS20050255
- ↑ Rittinger K, Walker PA, Eccleston JF, Smerdon SJ, Gamblin SJ. Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature. 1997 Oct 16;389(6652):758-62. PMID:9338791 doi:10.1038/39651
