4d6o

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<StructureSection load='4d6o' size='340' side='right'caption='[[4d6o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4d6o' size='340' side='right'caption='[[4d6o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4d6o]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D6O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4d6o]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfurococcus_mucosus Desulfurococcus mucosus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D6O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d6n|4d6n]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6o OCA], [https://pdbe.org/4d6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d6o RCSB], [https://www.ebi.ac.uk/pdbsum/4d6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d6o ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d6o OCA], [http://pdbe.org/4d6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d6o RCSB], [http://www.ebi.ac.uk/pdbsum/4d6o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d6o ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DMO1_DESMO DMO1_DESMO]] Endonuclease involved in intron homing. Recognizes a recognizes up to 20 bp of DNA in the 23S rRNA gene intron. It has a slow turnover rate and cuts the coding strand with a slight preference over the non-coding strand.
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[[https://www.uniprot.org/uniprot/DMO1_DESMO DMO1_DESMO]] Endonuclease involved in intron homing. Recognizes a recognizes up to 20 bp of DNA in the 23S rRNA gene intron. It has a slow turnover rate and cuts the coding strand with a slight preference over the non-coding strand.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Desulfurococcus mucosus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gomez, H]]
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[[Category: Synthetic construct]]
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[[Category: Marcaida, M J]]
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[[Category: Gomez H]]
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[[Category: Molina, R]]
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[[Category: Marcaida MJ]]
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[[Category: Montoya, G]]
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[[Category: Molina R]]
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[[Category: Orozco, M]]
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[[Category: Montoya G]]
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[[Category: Prieto, J]]
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[[Category: Orozco M]]
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[[Category: Redondo, P]]
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[[Category: Prieto J]]
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[[Category: Stella, S]]
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[[Category: Redondo P]]
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[[Category: Catalysis]]
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[[Category: Stella S]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Protein-dna interaction]]
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[[Category: X-ray crystallography]]
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Revision as of 07:49, 14 September 2022

THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MG (STATE 2)

PDB ID 4d6o

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