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Malate synthase

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<scene name='57/573146/Cv/10'>Acetyl-CoA binding site</scene>.
<scene name='57/573146/Cv/10'>Acetyl-CoA binding site</scene>.
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==3d structures of malate synthase==
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[[Malate synthase 3D structures]]
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</StructureSection>
</StructureSection>
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**[[1n8i]] – MtMS G + glyoxylate + Mg <br />
**[[1n8i]] – MtMS G + glyoxylate + Mg <br />
**[[5h8u]] – MtMS G + malate + Mg <br />
**[[5h8u]] – MtMS G + malate + Mg <br />
-
**[[56axe]] – MtMS G + acetyl CoA + Mg <br />
+
**[[6axe]] – MtMS G + acetyl CoA + Mg <br />
**[[5c7v]], [[5cah]], [[5cjm]], [[5e9x]] – MtMS G (mutant) + pyrrole derivative + Mg <br />
**[[5c7v]], [[5cah]], [[5cjm]], [[5e9x]] – MtMS G (mutant) + pyrrole derivative + Mg <br />
**[[5cew]] – MtMS G (mutant) + pyridine derivative + Mg <br />
**[[5cew]] – MtMS G (mutant) + pyridine derivative + Mg <br />
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**[[5cak]], [[5cbb]], [[5cc3]], [[5cc5]], [[5cc6]], [[5cc7]], [[5drc]], [[5dri]], [[5ecv]] – MtMS G (mutant) + indole derivative + Mg <br />
**[[5cak]], [[5cbb]], [[5cc3]], [[5cc5]], [[5cc6]], [[5cc7]], [[5drc]], [[5dri]], [[5ecv]] – MtMS G (mutant) + indole derivative + Mg <br />
**[[5t8g]] – MtMS G (mutant) + thiophene derivative + Mg <br />
**[[5t8g]] – MtMS G (mutant) + thiophene derivative + Mg <br />
 +
**[[6dnp]], [[6dlj]], [[6dko]], [[6c8p]], [[6c7b]], [[6c6o]], [[6c2x]], [[6ba7]], [[6axb]], [[6au9]] – MtMS G + diketoacid inhibitor + Mg <br />
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**[[6dl9]], [[6bu1]], [[6asu]], [[6as6]], [[6apz]] – MtMS G (mutant) + phenyldiketoacid inhibitor + Mg <br />
**[[3s9i]], [[3s9z]], [[3sad]], [[3saz]], [[3sb0]] – MtMS G (mutant) + inhibitor + Mg <br />
**[[3s9i]], [[3s9z]], [[3sad]], [[3saz]], [[3sb0]] – MtMS G (mutant) + inhibitor + Mg <br />
**[[3oyx]], [[3pug]] – HvMS G + glyoxylate + Mg – ''Haloferax volcanii''<br />
**[[3oyx]], [[3pug]] – HvMS G + glyoxylate + Mg – ''Haloferax volcanii''<br />

Revision as of 07:37, 27 October 2019

Structure of malate synthase G complex with CoA, malate, Hepes and Mg+2 ion (green) (PDB entry 2gq3)

Drag the structure with the mouse to rotate

3d structures of malate synthase

Updated on 27-October-2019

References

  1. Anstrom DM, Kallio K, Remington SJ. Structure of the Escherichia coli malate synthase G:pyruvate:acetyl-coenzyme A abortive ternary complex at 1.95 A resolution. Protein Sci. 2003 Sep;12(9):1822-32. PMID:12930982
  2. Anstrom DM, Remington SJ. The product complex of M. tuberculosis malate synthase revisited. Protein Sci. 2006 Aug;15(8):2002-7. PMID:16877713 doi:15/8/2002

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Michal Harel, Alexander Berchansky, Karsten Theis, Joel L. Sussman

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