Insulin 3D Structures
From Proteopedia
(Difference between revisions)
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* Insulin | * Insulin | ||
| - | **[[5bts]], [[4ak0]], [[2lgb]], [[1guj]], [[2c8r]], [[2c8q]], [[3i40]], [[3i3z]], [[5en9]], [[3zi3]] - hIns A chain + B chain – human<br /> | + | **[[5bts]], [[4ak0]], [[2lgb]], [[1guj]], [[2c8r]], [[2c8q]], [[3i40]], [[3i3z]], [[5en9]], [[3zi3]], [[6s34]], [[6h3m]] - hIns A chain + B chain – human<br /> |
| - | **[[3e7y]], [[3e7z]], [[2qiu]], [[1os3]], [[1os4]], [[1mso]], [[1g7a]], [[1g7b]], [[1trz]], [[4eww]], [[4ewx]], [[4ewz]], [[4ex0]], [[4ex1]], [[4exx]], [[4ey1]], [[4ey9]], [[4eyd]], [[4eyn]], [[4eyp]], [[4f0n]], [[4f0o]], [[4f1a]], [[4f1b]], [[4f1c]] [[4f1d]], [[4f1f]], [[4f1g]], [[4f4t]], [[4f4v]], [[4f51]], [[4f8f]], [[4fg3]], [[4p65]], [[2vjz]], [[2vk0]], [[3p33]], [[3w7y]], [[3w7z]], [[3w80]], [[5ems]], [[5e7w]], [[5co9]], [[5co6]], [[5co2]] - hIns A chain + B chain + Zn<br /> | + | **[[3e7y]], [[3e7z]], [[2qiu]], [[1os3]], [[1os4]], [[1mso]], [[1g7a]], [[1g7b]], [[1trz]], [[4eww]], [[4ewx]], [[4ewz]], [[4ex0]], [[4ex1]], [[4exx]], [[4ey1]], [[4ey9]], [[4eyd]], [[4eyn]], [[4eyp]], [[4f0n]], [[4f0o]], [[4f1a]], [[4f1b]], [[4f1c]] [[4f1d]], [[4f1f]], [[4f1g]], [[4f4t]], [[4f4v]], [[4f51]], [[4f8f]], [[4fg3]], [[4p65]], [[2vjz]], [[2vk0]], [[3p33]], [[3w7y]], [[3w7z]], [[3w80]], [[5ems]], [[5e7w]], [[5co9]], [[5co6]], [[5co2]], [[6gv0]] - hIns A chain + B chain + Zn<br /> |
**[[1fu2]], [[1fub]] - hIns A chain + B chain + Zn – powder diffraction<br /> | **[[1fu2]], [[1fub]] - hIns A chain + B chain + Zn – powder diffraction<br /> | ||
**[[5t7r]] - hIns A chain (mutant) + B chain<br /> | **[[5t7r]] - hIns A chain (mutant) + B chain<br /> | ||
**[[1b9e]], [[3u4n]], [[4iuz]], [[4une]], [[4ung]], [[4unh]] - hIns A chain + B chain (mutant)<br /> | **[[1b9e]], [[3u4n]], [[4iuz]], [[4une]], [[4ung]], [[4unh]] - hIns A chain + B chain (mutant)<br /> | ||
**[[3bxq]], [[1qj0]] – hIns A chain + B chain (mutant) + Zn | **[[3bxq]], [[1qj0]] – hIns A chain + B chain (mutant) + Zn | ||
| - | **[[3ir0]], [[3inc]], [[3ilg]], [[3exx]], [[2r34]], [[2r35]], [[2r36]], [[3tt8]], [[4rxw]], [[4fka]] - hIns A chain + B chain + non-Zn metal ion<br /> | + | **[[3ir0]], [[3inc]], [[3ilg]], [[3exx]], [[2r34]], [[2r35]], [[2r36]], [[3tt8]], [[4rxw]], [[4fka]], [[6p4z]] - hIns A chain + B chain + non-Zn metal ion<br /> |
**[[1jca]], [[1j73]], [[4efx]], - hIns A chain (mutant) + B chain + Zn<br /> | **[[1jca]], [[1j73]], [[4efx]], - hIns A chain (mutant) + B chain + Zn<br /> | ||
**[[5ena]], [[2ws4]] - hIns A chain + B chain (mutant)<br /> | **[[5ena]], [[2ws4]] - hIns A chain + B chain (mutant)<br /> | ||
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**[[1m5a]] - pIns A chain + B chain + Co<br /> | **[[1m5a]] - pIns A chain + B chain + Co<br /> | ||
**[[6ins]] – pIns single chain<br /> | **[[6ins]] – pIns single chain<br /> | ||
| - | **[[1aph]], [[1bph]], [[1cph]], [[1dph]], [[4bs3]], [[4i5y]], [[4i5z]], [[4ihn]], [[2bn1]], [[2bn3]] - bIns A chain + B chain – bovine<br /> | + | **[[1aph]], [[1bph]], [[1cph]], [[1dph]], [[4bs3]], [[4i5y]], [[4i5z]], [[4ihn]], [[2bn1]], [[2bn3]], [[6qrh]], [[6qrk]], [[6qq7]], [[6qqg]] - bIns A chain + B chain – bovine<br /> |
**[[2zp6]], [[4e7t]], [[4e7u]], [[4e7v]], [[4idw]], [[2a3g]], - bIns A chain + B chain + Zn <br /> | **[[2zp6]], [[4e7t]], [[4e7u]], [[4e7v]], [[4idw]], [[2a3g]], - bIns A chain + B chain + Zn <br /> | ||
**[[4m4f]], [[4m4h]], [[4m4i]], [[4m4j]], [[4m4l]], [[4m4m]] - bIns A chain + B chain + non-Zn metal ion<br /> | **[[4m4f]], [[4m4h]], [[4m4i]], [[4m4j]], [[4m4l]], [[4m4m]] - bIns A chain + B chain + non-Zn metal ion<br /> | ||
| - | Insulin structures using NMR | + | *Insulin structures using NMR |
**[[1sf1]], [[2aiy]], [[3aiy]], [[4aiy]], [[5aiy]], [[1xgl]], [[2mvc]], [[2kxk]], [[2m1e]], [[2m2m]], [[2m2n]], [[2m2o]], [[2m2p]], [[2hiu]], [[2jv1]] - hIns A chain + B chain – NMR<br /> | **[[1sf1]], [[2aiy]], [[3aiy]], [[4aiy]], [[5aiy]], [[1xgl]], [[2mvc]], [[2kxk]], [[2m1e]], [[2m2m]], [[2m2n]], [[2m2o]], [[2m2p]], [[2hiu]], [[2jv1]] - hIns A chain + B chain – NMR<br /> | ||
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**[[5miz]] - bIns A chain + B chain – NMR<br /> | **[[5miz]] - bIns A chain + B chain – NMR<br /> | ||
| - | + | *Insulin complexes | |
| - | Insulin complexes | + | |
**[[3brr]] - hIns A chain + B chain + sulfatide + Zn<br /> | **[[3brr]] - hIns A chain + B chain + sulfatide + Zn<br /> | ||
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**[[6ck2]] - hIns A chain + B chain (mutant) + phenol + ornithine + Zn<br /> | **[[6ck2]] - hIns A chain + B chain (mutant) + phenol + ornithine + Zn<br /> | ||
**[[1qiz]] - hIns A chain (mutant) + B chain (mutant) + resorcinol + Zn<br /> | **[[1qiz]] - hIns A chain (mutant) + B chain (mutant) + resorcinol + Zn<br /> | ||
| - | **[[1ev3]], [[1ev6]], [[1uz9]], [[4gbn]], [[4gbc]], [[4gbi]], [[4gbk]], [[4gbl]] - hIns A chain + B chain + cresol + Zn<br /> | + | **[[1ev3]], [[1ev6]], [[1uz9]], [[4gbn]], [[4gbc]], [[4gbi]], [[4gbk]], [[4gbl]], [[6gnq]] - hIns A chain + B chain + cresol + Zn<br /> |
**[[1zeh]] - hIns A chain (mutant) + B chain (mutant) + cresol + Zn<br /> | **[[1zeh]] - hIns A chain (mutant) + B chain (mutant) + cresol + Zn<br /> | ||
**[[1evr]], [[4ajx]], [[3zu1]] - hIns A chain + B chain + resorcinol + Zn<br /> | **[[1evr]], [[4ajx]], [[3zu1]] - hIns A chain + B chain + resorcinol + Zn<br /> | ||
**[[3q6e]] - hIns A chain + B chain + synthetic receptor<br /> | **[[3q6e]] - hIns A chain + B chain + synthetic receptor<br /> | ||
**[[2g54]], [[2g56]] - hIns B chain + insulin-degrading enzyme + Zn<br /> | **[[2g54]], [[2g56]] - hIns B chain + insulin-degrading enzyme + Zn<br /> | ||
| - | **[[6b3q]] - hIns A chain + B chain + insulin-degrading enzyme | + | **[[6b3q]] - hIns A chain + B chain + insulin-degrading enzyme<br /> |
| + | **[[6bfc]] - hIns A chain + B chain + insulin-degrading enzyme – Cryo EM<br /> | ||
**[[2wby]], [[2wc0]] - hIns A chain + B chain + insulin-degrading enzyme (mutant) + Zn<br /> | **[[2wby]], [[2wc0]] - hIns A chain + B chain + insulin-degrading enzyme (mutant) + Zn<br /> | ||
**[[3w11]], [[3w14]] - hIns A chain + B chain + insulin-degrading enzyme + antibody<br /> | **[[3w11]], [[3w14]] - hIns A chain + B chain + insulin-degrading enzyme + antibody<br /> | ||
**[[5wob]] - hIns A chain + B chain + insulin-degrading enzyme + antibody + Zn<br /> | **[[5wob]] - hIns A chain + B chain + insulin-degrading enzyme + antibody + Zn<br /> | ||
**[[4oga]] - hIns A chain + B chain + insulin receptor + antibody<br /> | **[[4oga]] - hIns A chain + B chain + insulin receptor + antibody<br /> | ||
| - | **[[6ce7]], [[6ce9]], [[6ceb]] - hIns A chain + B chain + insulin receptor – Cryo EM<br /> | + | **[[6ce7]], [[6ce9]], [[6ceb]], [[6hn5]] - hIns A chain + B chain + insulin receptor – Cryo EM<br /> |
**[[5mam]] - hIns A chain + B chain + serotonin + Zn<br /> | **[[5mam]] - hIns A chain + B chain + serotonin + Zn<br /> | ||
**[[5mt9]], [[5mt3]] - hIns A chain + B chain + serotonin + arginine + Zn<br /> | **[[5mt9]], [[5mt3]] - hIns A chain + B chain + serotonin + arginine + Zn<br /> | ||
Revision as of 09:29, 2 September 2019
(Updated on 02-September-2019)
