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Ion channels 3D structures

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(New page: == 3D structures of ion channels == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * Potassium channel See: [[Pota...)
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**[[3oxq]] - hCav2.1 α 1C subunit IQ domain+hCalmodulin<br />
**[[3oxq]] - hCav2.1 α 1C subunit IQ domain+hCalmodulin<br />
**[[2vay]], [[3oxq]] - hCav1.1 α 1S subunit IQ domain+hCalmodulin<br />
**[[2vay]], [[3oxq]] - hCav1.1 α 1S subunit IQ domain+hCalmodulin<br />
 +
**[[6kzo]] – hCav3.1C – Cryo EM <br />
 +
**[[6kzp]] – hCav3.1C + antagonist – Cryo EM <br />
**[[1hvd]], [[1hve]], [[1hvf]], [[1hvg]] – hAnnexin V (mutant)<br />
**[[1hvd]], [[1hve]], [[1hvf]], [[1hvg]] – hAnnexin V (mutant)<br />
**[[6jp5]], [[6jp8]] – rCav1.1 – rabbit – Cryo EM<br />
**[[6jp5]], [[6jp8]] – rCav1.1 – rabbit – Cryo EM<br />
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**[[5gjv]], [[3jbr]] – rCav1.1 α 2/δ 1 + α 1S + β 1 + γ 1 – Cryo EM<br />
**[[5gjv]], [[3jbr]] – rCav1.1 α 2/δ 1 + α 1S + β 1 + γ 1 – Cryo EM<br />
**[[5v2q]], [[5v2p]] - raCav1.2 1C + 2 - rat<br />
**[[5v2q]], [[5v2p]] - raCav1.2 1C + 2 - rat<br />
-
**[[5vov]], [[5vou]], [[5vot]], [[5kk2]] - raVDCC g 2 + glutamate receptor – Cryo EM<br />
+
**[[5vov]], [[5vou]], [[5vot]], [[5kk2]] - raVDCC γ 2 + glutamate receptor 2 – Cryo EM<br />
 +
**[[6njl]], [[6njm]], [[6njn]] - raVDCC γ 2 + glutamate receptor 1 + glutamate receptor 2 + a’/c’ auxiliary protein + antibody – Cryo EM<br />
 +
**[[6qkc]], [[6qkz]] - raVDCC γ 8 + glutamate receptor 1 + glutamate receptor 2 – Cryo EM<br />
**[[6c9a]], [[6c96]] – mTpc1 - mouse <br />
**[[6c9a]], [[6c96]] – mTpc1 - mouse <br />
**[[6c96]], [[6c9a]] – mTpc1 – Cryo EM <br />
**[[6c96]], [[6c9a]] – mTpc1 – Cryo EM <br />
Line 44: Line 48:
*See also [[Ryanodine receptor]]
*See also [[Ryanodine receptor]]
-
*Sodium channel
+
*Sodium channel; Domains – extracellular 30-157
**[[2kav]], [[2kbi]] - hNaV 1.2 α C-terminal EF-hand domain - NMR<br />
**[[2kav]], [[2kbi]] - hNaV 1.2 α C-terminal EF-hand domain - NMR<br />
Line 51: Line 55:
**[[6j8e]] - hNaV 2 + hNav 1.2 + Mu-conotoxin – Cryo EM<br />
**[[6j8e]] - hNaV 2 + hNav 1.2 + Mu-conotoxin – Cryo EM<br />
**[[6j8g]], [[6j8h]], [[6j8i]], [[6j8j]] - hNaV 2 + hNaV 1 + hNav 1.7 + toxin – Cryo EM<br />
**[[6j8g]], [[6j8h]], [[6j8i]], [[6j8j]] - hNaV 2 + hNaV 1 + hNav 1.7 + toxin – Cryo EM<br />
-
**[[4l1d]] - hNaV β 3 IG domain <br />
+
**[[6vrr]] - hNaV 2 (mutant)<br />
 +
**[[4l1d]] - hNaV β 3 extracellular domain <br />
**[[4mz2]] - hNaV β 4 extracellular domain <br />
**[[4mz2]] - hNaV β 4 extracellular domain <br />
-
**[[4mz3]] - hNaV β 4 extracellular domain (mutant)<br />
+
**[[4mz3]], [[6vsv]] - hNaV β 4 extracellular domain (mutant)<br />
**[[6mba]], [[6mc9]] – hNaV 1.4 C terminal + calmodulin <br />
**[[6mba]], [[6mc9]] – hNaV 1.4 C terminal + calmodulin <br />
 +
**[[6wth]] – hENAC ++g subunits + antibody – Cryo EM<br />
**[[4ovn]], [[5dbr]], [[4djc]], [[6mud]] – hNaV 1.5 α C terminal + calmodulin <br />
**[[4ovn]], [[5dbr]], [[4djc]], [[6mud]] – hNaV 1.5 α C terminal + calmodulin <br />
**[[4dck]], [[4jq0]] – hNaV 1.5 α C terminal + calmodulin + fibroblast growth factor <br />
**[[4dck]], [[4jq0]] – hNaV 1.5 α C terminal + calmodulin + fibroblast growth factor <br />
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**[[3t9n]], [[3udc]] – MscS – ''Thermoanaerobacter tengcongensis''<br />
**[[3t9n]], [[3udc]] – MscS – ''Thermoanaerobacter tengcongensis''<br />
**[[4hw9]] – MscS – ''Helicobacter pylori''<br />
**[[4hw9]] – MscS – ''Helicobacter pylori''<br />
 +
**[[6lyp]], [[6vxm]], [[6vxn]], [[6vxp]] – AtMsc-like (mutant) – Cryo EM<br />
* Chloride channel
* Chloride channel
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**[[2ahe]], [[2d2z]] – hClCh protein 4<br />
**[[2ahe]], [[2d2z]] – hClCh protein 4<br />
**[[2pfi]] - hClCh KA<br />
**[[2pfi]] - hClCh KA<br />
 +
**[[6y2h]] - hClCh protein 5<br />
**[[2j9l]], [[2ja3]] - hClCh protein 5 + nucleotide<br />
**[[2j9l]], [[2ja3]] - hClCh protein 5 + nucleotide<br />
**[[5tr1]], [[5tqq]] - bCIC (mutant) + antibody – bovine - Cryo EM<br />
**[[5tr1]], [[5tqq]] - bCIC (mutant) + antibody – bovine - Cryo EM<br />
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**[[2jk4]], [[2k4t]], [[5jdp]], [[5xdo]], [[5xdn]], [[6g73]], [[6g6u]] – hVDAC1<br />
**[[2jk4]], [[2k4t]], [[5jdp]], [[5xdo]], [[5xdn]], [[6g73]], [[6g6u]] – hVDAC1<br />
 +
**[[6tiq]] – hVDAC1 – NMR<br />
 +
**[[6tir]] – hVDAC1 + NAD – NMR<br />
**[[6djb]], [[5zsu]] – hVDAC1 subunit LRRC8A – Cryo EM<br />
**[[6djb]], [[5zsu]] – hVDAC1 subunit LRRC8A – Cryo EM<br />
 +
**[[6m04]] – hVDAC1 subunit LRRC8AD (mutant) – Cryo EM<br />
**[[3emn]], [[4c69]] – mVDAC1 <br />
**[[3emn]], [[4c69]] – mVDAC1 <br />
**[[6g9o]], [[6g9l]], [[6g8z]], [[6o00]], [[6nzz]], [[6nzw]] – mVDAC1 subunit LRRC8A – Cryo EM<br />
**[[6g9o]], [[6g9l]], [[6g8z]], [[6o00]], [[6nzz]], [[6nzw]] – mVDAC1 subunit LRRC8A – Cryo EM<br />
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**[[5lid]] – EchELIC + bromopromazine <br />
**[[5lid]] – EchELIC + bromopromazine <br />
**[[5sxv]] – EchELIC + inhibitor <br />
**[[5sxv]] – EchELIC + inhibitor <br />
 +
**[[6hk0]] – DcELIC (mutant) – ''Dickeya chrysanthemi''<br />
 +
**[[6hjx]], [[6hjy]], [[6ssi]], [[6ssp]] – DcELIC + nanobody <br />
 +
**[[6fl9]], [[6fli]], [[6fvq]], [[6fvr]], [[6fvs]] - ELIC – vent tica<br />
**[[3eam]], [[3ehz]], [[4hfi]], [[4il4]], [[4ilc]], [[4npp]], [[4npq]], [[4qh1]], [[4qh5]], [[4qh4]], [[6f7a]], [[6f16]], [[4zzc]], [[6hzw]] – GvGLIC – ''Gloeobacter violaceus''br />
**[[3eam]], [[3ehz]], [[4hfi]], [[4il4]], [[4ilc]], [[4npp]], [[4npq]], [[4qh1]], [[4qh5]], [[4qh4]], [[6f7a]], [[6f16]], [[4zzc]], [[6hzw]] – GvGLIC – ''Gloeobacter violaceus''br />
**[[3lsv]], [[3tls]], [[3tlt]], [[3tlu]], [[3tlv]], [[3tlw]], [[3uu3]], [[3uu4]], [[3uu5]], [[3uu6]], [[3uu8]], [[3uub]], [[3ei0]], [[4hfb]], [[4il9]], [[4ila]], [[4ilb]], [[4ire]], [[4lmj]], [[4lmk]], [[4lml]], [[5hcj]], [[5hcm]], [[5heg]], [[5heh]], [[5iux]], [[5v6o]], [[5v6n]], [[5nkj]], [[5njy]], [[5mzt]], [[5mzr]], [[5mzq]], [[4zzb]], [[6hy5]], [[6hy9]], [[6hya]], [[6hyr]], [[6hyv]], [[6hyw]], [[6hyx]], [[6hyz]], [[6hz0]], [[6hz1]], [[6hz3]], [[6emx]], [[6f0i]], [[6f0j]], [[6f0m]], [[6f0n]], [[6f0r]], [[6f0u]], [[6f0v]], [[6f0z]], [[6f10]], [[6f11]], [[6f12]], [[6f13]], [[6f15]], [[6f16]], [[6i08]] – GvGLIC (mutant)<br />
**[[3lsv]], [[3tls]], [[3tlt]], [[3tlu]], [[3tlv]], [[3tlw]], [[3uu3]], [[3uu4]], [[3uu5]], [[3uu6]], [[3uu8]], [[3uub]], [[3ei0]], [[4hfb]], [[4il9]], [[4ila]], [[4ilb]], [[4ire]], [[4lmj]], [[4lmk]], [[4lml]], [[5hcj]], [[5hcm]], [[5heg]], [[5heh]], [[5iux]], [[5v6o]], [[5v6n]], [[5nkj]], [[5njy]], [[5mzt]], [[5mzr]], [[5mzq]], [[4zzb]], [[6hy5]], [[6hy9]], [[6hya]], [[6hyr]], [[6hyv]], [[6hyw]], [[6hyx]], [[6hyz]], [[6hz0]], [[6hz1]], [[6hz3]], [[6emx]], [[6f0i]], [[6f0j]], [[6f0m]], [[6f0n]], [[6f0r]], [[6f0u]], [[6f0v]], [[6f0z]], [[6f10]], [[6f11]], [[6f12]], [[6f13]], [[6f15]], [[6f16]], [[6i08]] – GvGLIC (mutant)<br />
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**[[5j0z]] - GvGLIC + choline derivative<br />
**[[5j0z]] - GvGLIC + choline derivative<br />
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
**[[5l47]], [[5l4e]], [[5l4h]] - GvGLIC + barbiturate<br />
-
**[[6fl9]], [[6fli]], [[6fvq]], [[6fvr]], [[6fvs]] - STELIC – vent tica<br />
+
**[[6hj3]], [[6hjb]], [[6hji]], [[6hja]], [[6hjz]], [[6hpp]] - GvGLIC + carboxylate<br />
* Cyclic Nucleotide-Gated channel
* Cyclic Nucleotide-Gated channel
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**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
**[[2q0a]] - mCNGC 2 C-terminal (mutant)<br />
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
**[[3bpz]] - mCNGC 2 ligand-binding domain <br />
-
**[[5u6o]], [[5u6p]] – hCNGC 1 – Cryo EM<br />
+
**[[5u6o]], [[5u6p]], [[6uqf]], [[6uqg]] – hCNGC 1 – Cryo EM<br />
**[[2mpf]] – hCNGC 2 ligand-binding domain - NMR<br />
**[[2mpf]] – hCNGC 2 ligand-binding domain - NMR<br />
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
**[[5khg]], [[5khh]], [[5khi]], [[5khj]], [[5khk]] – mCNGC 2 ligand-binding domain + nucleotide<br />
**[[3swy]] – hCNGC 3 CLZ domain<br />
**[[3swy]] – hCNGC 3 CLZ domain<br />
 +
**[[6gyn]] – hCNGC 4 – Cryo EM<br />
 +
**[[6gyo]] – hCNGC 4 + cAMP – Cryo EM<br />
**[[3otf]] – hCNGC 4 ligand-binding domain<br />
**[[3otf]] – hCNGC 4 ligand-binding domain<br />
**[[2mng]] – hCNGC 4 ligand-binding domain - NMR<br />
**[[2mng]] – hCNGC 4 ligand-binding domain - NMR<br />
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**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
**[[3ij4]], [[2qts]], [[3s3w]], [[4nyk]], [[3ij4]], [[6ave]], [[5wku]], [[5wkv]], [[5wky]], [[5wkx]], [[6cmc]] – cASC – chicken<br />
 +
**[[6vtk]], [[6vtl]] – cASC – Cryo EM<br />
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
**[[3s3x]], [[4fz0]], [[4fz1]] – cASC + psalmotoxin<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
**[[4ntw]], [[4ntx]], [[4nty]] - cASC + neurotoxin + basic phospholipase A2<br />
Line 198: Line 215:
**[[2kqt]] - IVproton channel transmembrane domain + drug - NMR<br />
**[[2kqt]] - IVproton channel transmembrane domain + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
**[[2ly0]] - IVproton channel transmembrane domain (mutant) + drug - NMR<br />
-
**[[2rtf]] - IVproton channel + inhibitor - NMR<br />
+
**[[2rlf]] - IVproton channel + inhibitor - NMR<br />
**[[3c9j]] - IVproton channel transmembrane domain + inhibitor<br />
**[[3c9j]] - IVproton channel transmembrane domain + inhibitor<br />

Revision as of 08:35, 27 August 2020

3D structures of ion channels

Updated on 27-August-2020

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman

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